(2S)-2-[[(Benzyloxy)carbonyl]aMino]-5-hexenoic Acid tert-Butyl Ester

Base Information

Chemical Name:(2S)-2-[[(Benzyloxy)carbonyl]aMino]-5-hexenoic Acid tert-Butyl Ester
CAS No.:127623-77-2
Molecular Formula:C18H25NO4
Molecular Weight:319.401
Hs Code.:
Mol file:127623-77-2.mol

Synonyms:(2S)-2-[[(Benzyloxy)carbonyl]amino]-5-hexenoic Acid tert-Butyl Ester;

Suppliers and Price of (2S)-2-[[(Benzyloxy)carbonyl]aMino]-5-hexenoic Acid tert-Butyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2S)-2-[[(Benzyloxy)carbonyl]amino]-5-hexenoicAcidtert-ButylEster
10mg
$ 140.00

Medical Isotopes, Inc.
(2S)-2-[[(Benzyloxy)carbonyl]amino]-5-hexenoicAcidtert-ButylEster
100 mg
$ 2000.00

Medical Isotopes, Inc.
(2S)-2-[[(Benzyloxy)carbonyl]amino]-5-hexenoicAcidtert-ButylEster
10 mg
$ 625.00

Total 2 raw suppliers

Chemical Property of (2S)-2-[[(Benzyloxy)carbonyl]aMino]-5-hexenoic Acid tert-Butyl Ester

Chemical Property:

PSA：64.63000
LogP:3.98020
Solubility.:Dichloromethane, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

(2S)-2-[[(Benzyloxy)carbonyl]amino]-5-hexenoicAcidtert-ButylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (2S)-2-[[(Benzyloxy)carbonyl]amino]-5-hexenoic Acid tert-Butyl Ester is a reactant used in the preparation of the two collagen cross-links pyridinoline and deoxypyridinoline. It is also used in the preparation of acyl derivatives of N-hydroxypyridine-2-thione.

Technology Process of (2S)-2-[[(Benzyloxy)carbonyl]aMino]-5-hexenoic Acid tert-Butyl Ester

There total 11 articles about (2S)-2-[[(Benzyloxy)carbonyl]aMino]-5-hexenoic Acid tert-Butyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: 606148-70-3
tert-butyl (2S)-2-aminohex-5-enoate

: 127623-77-2
tert-butyl (S)-2-benzyloxycarbonylamino-6-hydroxyhex-5-enoate

Guidance literature:: In 1,4-dioxane; water; at 20 ℃; for 2.5h;
DOI:10.1016/S0957-4166(03)00400-2

Reference yield: 42.0%

: 112157-39-8
Nα-(Benzyloxycarbonyl)-L-lysine tert-butyl ester

: 127623-77-2
tert-butyl (S)-2-benzyloxycarbonylamino-6-hydroxyhex-5-enoate

: 495401-20-2
tert-butyl (S)-2-(((benzyloxy)carbonyl)amino)-6-hydroxyhexanoate

Guidance literature:: Nα-(Benzyloxycarbonyl)-L-lysine tert-butyl ester; With sodium nitrite; In water; acetic acid; at 20 ℃; for 4h;

With potassium hydroxide; In methanol;
DOI:10.1016/S0957-4166(02)00477-9

Reference yield: 28.0%

: 144787-23-5
2-((S)-1-(benzyloxycarbonylamino)-2-tert-butoxy-2-oxoethyl)pent-4-enoic acid

: 127623-77-2
tert-butyl (S)-2-benzyloxycarbonylamino-6-hydroxyhex-5-enoate

Guidance literature:: With 1-oxa-2-oxo-3-thiaindolizinium chloride; 2-methylpropan-2-thiol; In benzene; for 4h; Heating; Irradiation;
DOI:10.1016/S0040-4020(01)85140-1