5-<1-(4-chlorophenyl)-2-(3-chlorophenyl)ethyl>-2,4,6-trichloropyrimidine

Base Information

• Chemical Name: 5-<1-(4-chlorophenyl)-2-(3-chlorophenyl)ethyl>-2,4,6-trichloropyrimidine
• CAS No.: 170955-75-6
• Molecular Formula: C₁₈H₁₁Cl₅N₂
• Molecular Weight: 432.564
• Mol file: 170955-75-6.mol

Synonyms:

Chemical Property of 5-<1-(4-chlorophenyl)-2-(3-chlorophenyl)ethyl>-2,4,6-trichloropyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-<1-(4-chlorophenyl)-2-(3-chlorophenyl)ethyl>-2,4,6-trichloropyrimidine

There total 3 articles about 5-<1-(4-chlorophenyl)-2-(3-chlorophenyl)ethyl>-2,4,6-trichloropyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chlorobenzaldehyde (104-88-1) → 5-<1-(4-chlorophenyl)-2-(3-chlorophenyl)ethyl>-2,4,6-trichloropyrimidine (170955-75-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / H₂O

2: 2.) aq. HCl / 1.) THF, from 0 deg C to RT

3: 1.) POCl₃, 2.) PCl₅ / 1.) reflux, overnight, 2.) reflux, overnight

With hydrogenchloride; phosphorus pentachloride; trichlorophosphate; In water;

DOI:10.1016/S0223-5234(96)80010-9

Reference yield:

5-<1-(4-chlorophenyl)-2-(3-chlorophenyl)ethyl>barbituric acid (175693-00-2) → 5-<1-(4-chlorophenyl)-2-(3-chlorophenyl)ethyl>-2,4,6-trichloropyrimidine (170955-75-6)

Guidance literature:

With phosphorus pentachloride; trichlorophosphate; Yield given. Multistep reaction; 1.) 105 deg C, overnight, 2.) reflux, overnight;

DOI:10.1016/0223-5234(96)88279-1

Reference yield:

5-(4-chlorobenzylidene)barbituric acid (27402-31-9) → 5-<1-(4-chlorophenyl)-2-(3-chlorophenyl)ethyl>-2,4,6-trichloropyrimidine (170955-75-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.) aq. HCl / 1.) THF, from 0 deg C to RT

2: 1.) POCl₃, 2.) PCl₅ / 1.) reflux, overnight, 2.) reflux, overnight

With hydrogenchloride; phosphorus pentachloride; trichlorophosphate;

DOI:10.1016/S0223-5234(96)80010-9

upstream raw materials:

5-<1-(4-chlorophenyl)-2-(3-chlorophenyl)ethyl>barbituric acid

4-chlorobenzaldehyde

5-(4-chlorobenzylidene)barbituric acid