Bis(dimethylamino)methylphosphine

Base Information

• Chemical Name: Bis(dimethylamino)methylphosphine
• CAS No.: 14937-39-4
• Molecular Formula: C5H15 N2 P
• Molecular Weight: 134.161
• Hs Code.: 2929909090
• DSSTox Substance ID: DTXSID30933630
• Nikkaji Number: J960.317D
• Mol file: 14937-39-4.mol

Synonyms:Bis(dimethylamino)methylphosphine;14937-39-4;N-[dimethylamino(methyl)phosphanyl]-N-methylmethanamine;Phosphine, bis(dimethylamino)-methyl-;4534-85-4;BIS(DIMETHYLAMINO)-METHYLPHOSPHINE;Phosphonous diamide, N,N,N',N',P-pentamethyl-;N,N,N',N',1-pentamethylphosphinediamine;Methylbis(dimethylamino)phosphine;SCHEMBL10785940;DTXSID30933630;Phosphonous diamide, pentamethyl-;AKOS006281480;bis(dimethylamino)phosphonium methylide;N,N,N',N',p-Pentamethylphosphonous diamide;FT-0695149;N,N,N',N',p-Pentamethylphosphonous diamide #

Chemical Property of Bis(dimethylamino)methylphosphine

Chemical Property:

• Vapor Pressure: 7.17mmHg at 25°C
• Boiling Point: 137.1°Cat760mmHg
• Flash Point: 36.7°C
• PSA: 20.07000
• Density: g/cm³
• LogP: 1.05130
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 134.097285485
• Heavy Atom Count: 8
• Complexity: 55.4

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)P(C)N(C)C

Technology Process of Bis(dimethylamino)methylphosphine

There total 8 articles about Bis(dimethylamino)methylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

bis[bis(dimethylamino)phosphinyl]methane (63366-54-1) → Cyclenphosphorane (64317-97-1) + methyl-bis(dimethylamino)phosphine (14937-39-4)

Guidance literature:

With dimethyl amine; 1,4,7,10-tetraazacyclododecan; In toluene; at 115 ℃; for 0.916667h;

DOI:10.1080/10426509708044207

Reference yield: 71.0%

1,4,7,10-tetraazacyclododecan (294-90-6) → Cyclenphosphorane (64317-97-1) + methyl-bis(dimethylamino)phosphine (14937-39-4)

Guidance literature:

With bis[bis(dimethylamino)phosphinyl]methane; dimethyl amine; In toluene; at 115 ℃; for 0.916667h;

DOI:10.1080/10426509708044207

Reference yield:

C32H36N3O5P (91275-57-9) → methyl-bis(dimethylamino)phosphine (14937-39-4) + C59H57N4O10P (91304-83-5)

Guidance literature:

With 1,2,3-Benzotriazole; In chloroform; for 4h;

DOI:10.1016/S0040-4039(01)80180-5

upstream raw materials:

methyldibromophosphine

dimethyl amine

bis(N,N-dimethylamino)chlorophosphine

methyllithium

Downstream raw materials:

dimethyl methylphosphonite

C₁₂H₂₃N₃O₂P₂

Dianilino-methyl-phosphin

methylphosphonous acid diphenyl ester

Refernces

• 1、 Holmes,Wagner. "". . p. 357,360. Retrieved 1962.
• 2、 Jaeger, Alfred,Engels, Joachim. "SYNTHESIS OF DEOXYNUCLEOSIDE METHYLPHOSPHONATES VIA A PHOSPHONAMIDITE APPROACH". . p. 1437 - 1440. Retrieved 2007/10/02.