Technology Process of 1,3,5(10)-estratriene-2,3,6α,7α,17β-pentaol 2,3,17-tribenzyl ether
There total 9 articles about 1,3,5(10)-estratriene-2,3,6α,7α,17β-pentaol 2,3,17-tribenzyl ether which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 1.) pyridinium chloride / 1.) 1 h, 200 deg C; 2.) pyridine, 1 h, r.t.
2: 56 percent / CrO3 / acetic acid; H2O / 1 h / 0 °C
3: 54 percent / NaBH4 / tetrahydrofuran; ethanol / 1.5 h
4: 93 percent / K2CO3 / dimethylformamide / 16 h
5: 89 percent / KOH / methanol / 2 h
6: 57 percent / 50percent NaH / dimethylformamide
7: CH2Cl2 / 0.17 h / 0 °C
8: 1 N NaOH / tetrahydrofuran; methanol / 1 h
With
chromium(VI) oxide; potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; pyridine hydrochloride; sodium hydride; potassium carbonate;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1002/recl.19831021003
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 56 percent / CrO3 / acetic acid; H2O / 1 h / 0 °C
2: 54 percent / NaBH4 / tetrahydrofuran; ethanol / 1.5 h
3: 93 percent / K2CO3 / dimethylformamide / 16 h
4: 89 percent / KOH / methanol / 2 h
5: 57 percent / 50percent NaH / dimethylformamide
6: CH2Cl2 / 0.17 h / 0 °C
7: 1 N NaOH / tetrahydrofuran; methanol / 1 h
With
chromium(VI) oxide; potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; sodium hydride; potassium carbonate;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1002/recl.19831021003
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 57 percent / 50percent NaH / dimethylformamide
2: CH2Cl2 / 0.17 h / 0 °C
3: 1 N NaOH / tetrahydrofuran; methanol / 1 h
With
sodium hydroxide; sodium hydride;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/recl.19831021003
