5-(Hydroxy-methoxy-phosphoryl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 5-(4-methoxy-benzyloxycarbonyl)-pentyl ester

Base Information

Chemical Name:5-(Hydroxy-methoxy-phosphoryl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 5-(4-methoxy-benzyloxycarbonyl)-pentyl ester
CAS No.:205752-53-0
Molecular Formula:C₂₉H₃₅N₂O₁₀P
Molecular Weight:602.578
Hs Code.:

5-(Hydroxy-methoxy-phosphoryl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 5-(4-methoxy-benzyloxycarbonyl)-pentyl ester

Synonyms:

Suppliers and Price of 5-(Hydroxy-methoxy-phosphoryl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 5-(4-methoxy-benzyloxycarbonyl)-pentyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-(Hydroxy-methoxy-phosphoryl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 5-(4-methoxy-benzyloxycarbonyl)-pentyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(Hydroxy-methoxy-phosphoryl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 5-(4-methoxy-benzyloxycarbonyl)-pentyl ester

There total 7 articles about 5-(Hydroxy-methoxy-phosphoryl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 5-(4-methoxy-benzyloxycarbonyl)-pentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1191-25-9
6-Hydroxyhexanoic acid

: 205752-53-0
5-(Hydroxy-methoxy-phosphoryl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 5-(4-methoxy-benzyloxycarbonyl)-pentyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: dimethylformamide / Ambient temperature

2: 98 percent / diisopropyl azopdicarboxylate, PPh₃ / tetrahydrofuran / Ambient temperature

3: 1.) tert-butylamine, 2.) ion exchange resin (DOWEX (50W-X₈)) / 1.) from 50 to 60 deg C, 7 d, 2.) MeOH

With di-isopropyl azodicarboxylate; ion exchange resin (DOWEX (50W-X₈)); tert-butylamine; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1248/cpb.46.518

Reference yield:

: 824-94-2
p-methoxybenzyl chloride

: 205752-53-0
5-(Hydroxy-methoxy-phosphoryl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 5-(4-methoxy-benzyloxycarbonyl)-pentyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: dimethylformamide / Ambient temperature

2: 98 percent / diisopropyl azopdicarboxylate, PPh₃ / tetrahydrofuran / Ambient temperature

3: 1.) tert-butylamine, 2.) ion exchange resin (DOWEX (50W-X₈)) / 1.) from 50 to 60 deg C, 7 d, 2.) MeOH

With di-isopropyl azodicarboxylate; ion exchange resin (DOWEX (50W-X₈)); tert-butylamine; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1248/cpb.46.518

Reference yield:

: 205752-51-8
6-Hydroxy-hexanoic acid 4-methoxy-benzyl ester

: 205752-53-0
5-(Hydroxy-methoxy-phosphoryl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 5-(4-methoxy-benzyloxycarbonyl)-pentyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / diisopropyl azopdicarboxylate, PPh₃ / tetrahydrofuran / Ambient temperature

2: 1.) tert-butylamine, 2.) ion exchange resin (DOWEX (50W-X₈)) / 1.) from 50 to 60 deg C, 7 d, 2.) MeOH

With di-isopropyl azodicarboxylate; ion exchange resin (DOWEX (50W-X₈)); tert-butylamine; triphenylphosphine; In tetrahydrofuran;
DOI:10.1248/cpb.46.518