N-t-butoxycarbonyl-4-(3-(2-fluoroethoxy)phenyl)piperazin-1-ylbutanamine

Base Information

• Chemical Name: N-t-butoxycarbonyl-4-(3-(2-fluoroethoxy)phenyl)piperazin-1-ylbutanamine
• CAS No.: 1137920-98-9
• Molecular Formula: C₂₁H₃₄FN₃O₃
• Molecular Weight: 395.518
• Mol file: 1137920-98-9.mol

Synonyms:

Chemical Property of N-t-butoxycarbonyl-4-(3-(2-fluoroethoxy)phenyl)piperazin-1-ylbutanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-t-butoxycarbonyl-4-(3-(2-fluoroethoxy)phenyl)piperazin-1-ylbutanamine

There total 1 articles about N-t-butoxycarbonyl-4-(3-(2-fluoroethoxy)phenyl)piperazin-1-ylbutanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-fluoroethyl methanesulfonate (461-31-4) + C19H31N3O3 → N-t-butoxycarbonyl-4-(3-(2-fluoroethoxy)phenyl)piperazin-1-ylbutanamine (1137920-98-9)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 65 ℃; for 3h;

DOI:10.1016/j.bmc.2008.11.044

Reference yield:

N-t-butoxycarbonyl-4-(3-(2-fluoroethoxy)phenyl)piperazin-1-ylbutanamine (1137920-98-9) → 4-(3-(2-fluoroethoxy)phenyl)-1-piperazinebutanamine hydrochloride (1137921-02-8)

Guidance literature:

With hydrogenchloride; water; In 1,4-dioxane; at 20 ℃; for 3h;

DOI:10.1016/j.bmc.2008.11.044

upstream raw materials:

2-fluoroethyl methanesulfonate

Downstream raw materials:

4-(3-(2-fluoroethoxy)phenyl)-1-piperazinebutanamine hydrochloride