461-31-4

Usage

Uses

Used in Pharmaceutical Industry:
Methanesulfonic acid 2-fluoroethyl ester is used as a reagent in organic synthesis for the production of pharmaceutical compounds. The presence of the fluorine atom in the molecule can enhance the reactivity and properties of the synthesized compounds, making them more effective for various medical applications.
Used in Agrochemical Industry:
Methanesulfonic acid 2-fluoroethyl ester is also used as a reagent in the production of agrochemicals. The fluorine atom in the molecule can improve the reactivity and properties of the synthesized agrochemicals, making them more effective for agricultural purposes.
It is important to handle Methanesulfonic acid 2-fluoroethyl ester with care, as it can be corrosive and harmful if not properly managed. Additionally, all safety guidelines and lab protocols should be followed when working with Methanesulfonic acid 2-fluoroethyl ester to prevent any accidents or injuries.

InChI:InChI=1/C3H7FO3S/c1-8(5,6)7-3-2-4/h2-3H2,1H3

Upstream product

• 371-62-0 2-fluoroethanol 
• 124-63-0 methanesulfonyl chloride 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 947371-47-3 (2S,3S)-2-(N-tert-butoxycarbonyl)amino-3-(3-cyanophenyl)-4-[4-(2-fluoroethoxy)phenyl]butane 
• 433939-10-7 3-chloro-5-(2-fluoroethoxy)benzaldehyde 
• 820215-85-8 ethyl 3-{4-(2-fluoroethoxy)-3-methoxy-phenyl}propionate 
• 1137920-96-7 N-t-butoxycarbonyl-4-(2-(2-fluoroethoxy)phenyl)piperazin-1-ylbutanamine 
• 1137920-98-9 N-t-butoxycarbonyl-4-(3-(2-fluoroethoxy)phenyl)piperazin-1-ylbutanamine 
• 1245710-91-1 (E)-4-[(2-fluoroethyl)methylamino]-but-2-enoic acid [4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl]amide 
• 1313378-65-2 N-[4-(3-chloro-4-fluorophenylamino)-3-cyano-7-(2-fluoro-ethoxy)-quinolin-6-yl]-acetamide 
• 1248621-05-7 2-(4-nitrophenyl)-6-(2-fluoroethoxy)benzothiophene 
• 1342830-86-7 1-cyclopropyl-3-(3-fluoro-4-(2-(5-((4-(2-fluoroethyl)piperazin-1-yl)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)urea 
• 462-31-7 thioacetic acid-2-fluoroethyl ester 
• 1038474-00-8 (S)-methyl 2-[(tert-butoxycarbonyl)amino]-3-[4-(2-fluoroethoxy)phenyl]propanoate 

Relevant academic research and scientific papers

SUBSTITUTED GUANIDINE COMPOUND

The present invention provides a compound of general formula (I) (wherein X is as described in the present description and claims), or a pharmacologically acceptable salt thereof, and a pharmaceutical composition containing that compound.

SUBSTITUTED GUANIDINE DERIVATIVE

The present invention provides a compound of general formula (I) (wherein, R1, X, p and q are as described in the present description and claims), or a pharmacologically acceptable salt thereof, and a pharmaceutical composition containing that compound.

Nitrogen-containing, fluoroalkyl sulfonyl chloride method for the preparation of (by machine translation)

The invention discloses a nitrogen-containing, fluoroalkyl sulfonyl chloride method for preparing, by containing nitrogen/perfluoroalkyl alcohol as the raw material, under the alkaline condition and a sulfonyl chloride the reaction produces the corresponding nitrogen-containing/perfluoroalkyl sulfonate ester, then nitrogen-containing/perfluoroalkyl sulfonate ester with a thio acetic acid potassium generating affinity substitution reaction to produce the nitrogen-containing/Fluoalkyl thiophosphoro acetate, then the chlorine treatment to obtain nitrogen-containing/fluoroalkyl sulfonyl chloride. The synthesis of this invention containing nitrogen (fluoro) alkyl sulfonyl chloride, the compound is a drug, pesticide research and development and production of important pharmaceutical intermediate, the compound of preparation of the alkyl sulfonyl chloride synthesis of pharmaceutical intermediates database, to the market to provide alkyl sulfonyl chloride can be synthetic fragment. Raw materials used in the present invention chemical reagent is commercially available, low cost, short synthetic route, high yield, high product purity chemical, provides high-purity products, so as to obtain higher economic benefits. (by machine translation)

SUBSTITUTED IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS TROPOMYOSIN RECEPTOR KINASE A (TrkA) INHIBITORS

The present application relates to a series of substituted imidazo[1,2-a]pyridine compounds of formula (I), pharmaceutically acceptable salts, pharmaceutically acceptable solvates or stereoisomers thereof, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.

IMAGING NEURAL ACTIVITY

The present invention provides a novel radiofluorinated compound for imaging voltage-gated sodium channels (VGSCs) that is more straightforward to synthesise than the known radiofluorinated phenoxyphenyl pyrazole carboxylic acid compounds. The compound of the present invention demonstrates specific uptake and retention in key tissues as well as good in vivo stability. Also provided by the present invention is a radiopharmaceutical composition comprising the radiofluorinated compound of the invention, precursor compounds and methods for the synthesis of said radiofluorinated compound, and methods for using said radiofluorinated compound.

Inhibitors of Protein Tyrosine Kinase Activity

This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling. The invention also provides compounds, compositions and methods for treating cell proliferative diseases and conditions and ophthalmic diseases, disorders and conditions.

OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION

ABSTRACT The present invention provides a oxazole compound represented by Formula (1), or a salt thereof: wherein R1 is an aryl group which may have one or more substituents; R2 is an aryl group or a nitrogen atom-containing heterocyclic group each of which may have one or more substituents; and W is a divalent group represented by -Y1-A1- or -Y2-C(=O)- wherein Y1 is a group such as -C(=O)-, A1 is a group such as a lower alkylene group, and Y2 is a group such as a piperazinediyl group. The oxazole compound has a specific inhibitory action against phosphodiesterase 4.

NEW COMPOUNDS, PROCESS FOR THEIR PREPARATION, INTERMEDIATES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OF 5-HT6 MEDIATED DISORDERS SUCH AS ALZHEIMER'S DISEASE, COGNITIVE DISORDERS, COGNITIVE IMPAIRMENT ASSOCIATED WITH SCHIZOPHRENIA, OBESI

The present invention relates to new compounds of formula (I), or salts, solvates or solvated salts thereof, process for their preparation and to new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and

AMIDES AND METHOD FOR PLANT DISEASE CONTROL WITH THE SAME

N-(α-cyanobenzyl)amide compounds represented by the formula (1): wherein R1 represents a hydrogen atom; a halogen atom; a C1-C6 alkyl group optionally substituted with a halogen atom or the like; or the like, R2 represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group or the like, R3 represents a hydrogen atom or the like, R4 represents a C1-C4 alkyl group, a C3-C4 alkenyl group or the like, R5 represents a C1-C4 alkyl group, a C3-C4 alkenyl group, or the like, R6 represents a hydrogen atom or the like, R7 represents a hydrogen atom or the like, R8 represents a hydrogen atom or the like, R9 represents a hydrogen atom or the like, R10 represents a hydrogen atom or the like, R11 represents a hydrogen atom or the like, and R12 represents a hydrogen atom or the like, have excellent control activities against plant diseases.