Technology Process of ((2R,3S,6R)-3-acetoxy-6-(m-tolyl)-3,6-dihydro-2H-pyran-2-yl)methyl acetate
There total 5 articles about ((2R,3S,6R)-3-acetoxy-6-(m-tolyl)-3,6-dihydro-2H-pyran-2-yl)methyl acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1,10-Phenanthroline; oxygen; palladium diacetate;
In
acetic acid;
at 65 ℃;
for 4h;
Overall yield = 84 %; Overall yield = 45 mg;
DOI:10.1021/jo401032r
- Guidance literature:
-
Multi-step reaction with 6 steps
1: dipyridinium dichromate / acetic acid; ethyl acetate
2: 1H-imidazole / N,N-dimethyl-formamide
3: cerium(III) chloride; sodium tetrahydroborate
4: tetrabutyl ammonium fluoride / tetrahydrofuran
5: pyridine
6: 1,10-Phenanthroline; palladium diacetate; oxygen / acetic acid / 4 h / 65 °C
With
1H-imidazole; sodium tetrahydroborate; dipyridinium dichromate; 1,10-Phenanthroline; cerium(III) chloride; tetrabutyl ammonium fluoride; oxygen; palladium diacetate;
In
tetrahydrofuran; pyridine; acetic acid; ethyl acetate; N,N-dimethyl-formamide;
6: |Heck Reaction;
DOI:10.1021/jo401032r
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1H-imidazole / N,N-dimethyl-formamide
2: cerium(III) chloride; sodium tetrahydroborate
3: tetrabutyl ammonium fluoride / tetrahydrofuran
4: pyridine
5: 1,10-Phenanthroline; palladium diacetate; oxygen / acetic acid / 4 h / 65 °C
With
1H-imidazole; sodium tetrahydroborate; 1,10-Phenanthroline; cerium(III) chloride; tetrabutyl ammonium fluoride; oxygen; palladium diacetate;
In
tetrahydrofuran; pyridine; acetic acid; N,N-dimethyl-formamide;
5: |Heck Reaction;
DOI:10.1021/jo401032r
