4,5-dimethoxy-2-nitrobenzyl phthalimide

Base Information

• Chemical Name: 4,5-dimethoxy-2-nitrobenzyl phthalimide
• CAS No.: 35970-04-8
• Molecular Formula: C₁₇H₁₄N₂O₆
• Molecular Weight: 342.308
• Mol file: 35970-04-8.mol

Synonyms:

Chemical Property of 4,5-dimethoxy-2-nitrobenzyl phthalimide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5-dimethoxy-2-nitrobenzyl phthalimide

There total 2 articles about 4,5-dimethoxy-2-nitrobenzyl phthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-nitroveratrylbromide (53413-67-5) + potassium phtalimide (1074-82-4) → 4,5-dimethoxy-2-nitrobenzyl phthalimide (35970-04-8)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 18h;

DOI:10.1039/b600304d

Reference yield:

2-(hydroxymethyl)-1H-isoindole-1,3(2H)-dione (118-29-6) + 3,4-dimethoxynitrobenzene (709-09-1) → 4,5-dimethoxy-2-nitrobenzyl phthalimide (35970-04-8)

Guidance literature:

With sulfuric acid; water;

DOI:10.1021/ja01163a070

Reference yield:

4,5-dimethoxy-2-nitrobenzyl phthalimide (35970-04-8) → (4,5-dimethoxy-2-nitrophenyl)methanamine (123330-73-4)

Guidance literature:

With ethanol; hydrazine hydrate; anschliessend mit konz. wss.HCl;

DOI:10.1021/ja01163a070

upstream raw materials:

2-(hydroxymethyl)-1H-isoindole-1,3(2H)-dione

3,4-dimethoxynitrobenzene

6-nitroveratrylbromide

potassium phtalimide

Downstream raw materials:

(4,5-dimethoxy-2-nitrophenyl)methanamine

2-amino-4,5-dimethoxy-benzylamine

N-(4,5-dimethoxy-2-nitro-benzyl)-succinimide

(4,5-dimethoxy-2-nitro-benzyl)-urea

Refernces