C₂₇H₃₇N₅O₂

Base Information

• Chemical Name: C₂₇H₃₇N₅O₂
• CAS No.: 1191058-58-8
• Molecular Formula: C₂₇H₃₇N₅O₂
• Molecular Weight: 463.623
• Mol file: 1191058-58-8.mol

Synonyms:

Chemical Property of C₂₇H₃₇N₅O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₂₇H₃₇N₅O₂

There total 1 articles about C₂₇H₃₇N₅O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

endo-1-(8-azabicyclo[3.2.1]oct-3-yl)-2-methyl-1H-benzimidazole (478696-46-7) + diethylaluminium cyanide (5804-85-3) + N-(tert-butoxycarbonyl)-4-aminocyclohexanone (179321-49-4) → C27H37N5O2 (1191058-58-8)

Guidance literature:

endo-1-(8-azabicyclo[3.2.1]oct-3-yl)-2-methyl-1H-benzimidazole; N-(tert-butoxycarbonyl)-4-aminocyclohexanone; With titanium(IV) isopropylate; In 1,2-dichloro-ethane; at 20 - 80 ℃; for 19h;

diethylaluminium cyanide; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1016/j.bmcl.2009.07.074

Reference yield:

C27H37N5O2 (1191058-58-8) + methylmagnesium bromide (75-16-1) → C27H40N4O2 + C27H40N4O2

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 5h;

DOI:10.1016/j.bmcl.2009.07.074

upstream raw materials:

endo-1-(8-azabicyclo[3.2.1]oct-3-yl)-2-methyl-1H-benzimidazole

diethylaluminium cyanide

N-(tert-butoxycarbonyl)-4-aminocyclohexanone