4H-Pyrido[3,4-b]indol-4-one, 1,2,3,9-tetrahydro-2-(phenylmethyl)-

Base Information

Chemical Name:4H-Pyrido[3,4-b]indol-4-one, 1,2,3,9-tetrahydro-2-(phenylmethyl)-
CAS No.:130452-16-3
Molecular Formula:C18H16N2O
Molecular Weight:276.338
Hs Code.:
DSSTox Substance ID:DTXSID30451420
Nikkaji Number:J659.462J
Wikidata:Q82271432

Synonyms:130452-16-3;2-benzyl-2,3-dihydro-1H-pyrido[3,4-b]indol-4(9H)-one;4H-Pyrido[3,4-b]indol-4-one, 1,2,3,9-tetrahydro-2-(phenylmethyl)-;DTXSID30451420;2-Benzyl-1,2-dihydro-beta-carbolin-4(3H)-one;2-benzyl-1,2,3,9-tetrahydro-4H-beta-carbolin-4-one;2-benzyl-3,9-dihydro-1H-pyrido[5,4-b]indol-4-one

Suppliers and Price of 4H-Pyrido[3,4-b]indol-4-one, 1,2,3,9-tetrahydro-2-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4H-Pyrido[3,4-b]indol-4-one, 1,2,3,9-tetrahydro-2-(phenylmethyl)-

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:276.126263138
Heavy Atom Count:21
Complexity:391

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=C(C(=O)CN1CC3=CC=CC=C3)C4=CC=CC=C4N2

Technology Process of 4H-Pyrido[3,4-b]indol-4-one, 1,2,3,9-tetrahydro-2-(phenylmethyl)-

There total 4 articles about 4H-Pyrido[3,4-b]indol-4-one, 1,2,3,9-tetrahydro-2-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 140840-87-5
1-benzyl-3-(o-bromoanilino)-3,4-dehydro-5-oxopiperidine

: 130452-16-3
2-benzyl-4-oxo-1,2,3,4-tetrahydro-β-carboline

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; In N,N,N,N,N,N-hexamethylphosphoric triamide; at 140 ℃; for 2h;
DOI:10.1055/s-1995-3926

Reference yield: 25.0%

: 73385-16-7
1-benzyl-3-anilino-5-oxo-3,4-dehydropiperidine

: 130452-16-3
2-benzyl-4-oxo-1,2,3,4-tetrahydro-β-carboline

Guidance literature:: With palladium diacetate; In acetonitrile; for 6h; Product distribution; other enaminones;
DOI:10.3987/COM-90-5379

Reference yield:

: 50866-56-3
1-(benzyl)piperidin-3,5-dione

: 130452-16-3
2-benzyl-4-oxo-1,2,3,4-tetrahydro-β-carboline

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) trifluoroacetic acid, N-chlorosuccinimide, dimethyl sulphide / 1.) CH₂Cl₂, -20 deg C, 2.) CH₂Cl₂, RT, 3 h

2: 1.) NaH, 2.) CuI / 1.) HMPA, RT, 30 min, 2.) HMPA, 120 deg C, 2 h

With N-chloro-succinimide; copper(l) iodide; dimethylsulfide; sodium hydride; trifluoroacetic acid;