Acetic acid, (acetyloxy)[(diphenylmethylene)amino]-, methyl ester

Base Information

• Chemical Name: Acetic acid, (acetyloxy)[(diphenylmethylene)amino]-, methyl ester
• CAS No.: 130551-77-8
• Molecular Formula: C18H17NO4
• Molecular Weight: 311.337
• DSSTox Substance ID: DTXSID30446598
• Nikkaji Number: J1.888.275B
• Mol file: 130551-77-8.mol

Synonyms:130551-77-8;Acetic acid, (acetyloxy)[(diphenylmethylene)amino]-, methyl ester;SCHEMBL9862413;DTXSID30446598;N-Benzhydrylidene-2-acetoxyglycine methyl ester

Chemical Property of Acetic acid, (acetyloxy)[(diphenylmethylene)amino]-, methyl ester

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 311.11575802
• Heavy Atom Count: 23
• Complexity: 414

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC(C(=O)OC)N=C(C1=CC=CC=C1)C2=CC=CC=C2

Technology Process of Acetic acid, (acetyloxy)[(diphenylmethylene)amino]-, methyl ester

There total 1 articles about Acetic acid, (acetyloxy)[(diphenylmethylene)amino]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

methyl N-(diphenylmethylene)glycinate (81167-39-7) + acetic acid (64-19-7,77671-22-8) → Acetoxy-(benzhydrylidene-amino)-acetic acid methyl ester (130551-77-8)

Guidance literature:

With N,N,N,N-tetraethylammonium tetrafluoroborate; In acetonitrile; Electrochemical reaction;

DOI:10.1016/S0040-4039(03)00548-3

Reference yield: 87.0%

Acetoxy-(benzhydrylidene-amino)-acetic acid methyl ester (130551-77-8) + malonic acid dimethyl ester (108-59-8) → trimethyl 2-<(diphenylmethylene)amino>-1,1,2-ethanetricarboxylate (130946-35-9)

Guidance literature:

With palladium diacetate; sodium hydride; 1,4-di(diphenylphosphino)-butane; In acetonitrile; at 25 ℃; for 5h; Product distribution; various bis-phosphines, various product yields;

DOI:10.1016/0040-4039(95)00795-E

Reference yield:

methyl N-(diphenylmethylene)glycinate (81167-39-7) + Acetoxy-(benzhydrylidene-amino)-acetic acid methyl ester (130551-77-8) → meso-dimethyl-3-amino-N,N'-bis(diphenylmethylene)aspartate + (R,R)-dimethyl-3-amino-N,N'-bis(diphenylmethylene)aspartate + (S,S)-dimethyl-3-amino-N,N'-bis(diphenylmethylene)aspartate

Guidance literature:

With sodium hydride; palladium diacetate; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); In acetonitrile; at 20 ℃; for 20h;

DOI:10.1016/S0040-4039(03)01122-5

upstream raw materials:

methyl N-(diphenylmethylene)glycinate

acetic acid

Downstream raw materials:

trimethyl 2-<(diphenylmethylene)amino>-1,1,2-ethanetricarboxylate

2-(Benzhydrylidene-amino)-3-benzyloxycarbonyl-succinic acid 4-benzyl ester 1-methyl ester

methyl 2-((diphenylmethylene)amino)-2-(o-tolyl)acetate

methyl N^α-(diphenylmethylene)-DL-phenylglycinate