methyl 2-chloro-6-methoxy-cis-cinnamate

Base Information

• Chemical Name: methyl 2-chloro-6-methoxy-cis-cinnamate
• CAS No.: 85995-43-3
• Molecular Formula: C₁₁H₁₁ClO₃
• Molecular Weight: 226.66
• Mol file: 85995-43-3.mol

Synonyms:

Chemical Property of methyl 2-chloro-6-methoxy-cis-cinnamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-chloro-6-methoxy-cis-cinnamate

There total 1 articles about methyl 2-chloro-6-methoxy-cis-cinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methanol (67-56-1) + 2-chloro-6-methoxy-cis-cinnamic acid (85995-42-2) → methyl 2-chloro-6-methoxy-cis-cinnamate (85995-43-3)

Guidance literature:

With thionyl chloride; for 3h; Heating;

DOI:10.1021/jo00163a032

Reference yield:

methyl 2-chloro-6-methoxy-cis-cinnamate (85995-43-3) → methyl 2-chloro-6-methoxy-trans-cinnamate (85995-44-4)

Guidance literature:

With iodine; In toluene; for 24h; Yield given; Heating;

DOI:10.1021/jo00163a032

Reference yield:

methyl 2-chloro-6-methoxy-cis-cinnamate (85995-43-3) → 2,6-dimethoxy-cis-cinnamic acid (38489-75-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 mg / benzene / 46 h / Irradiation

2: 60 percent / 10percent NaOH / H₂O / 100 °C

With sodium hydroxide; In water; benzene;

DOI:10.1021/jo00163a032

upstream raw materials:

methanol

2-chloro-6-methoxy-cis-cinnamic acid

Downstream raw materials:

5-methoxycoumarin

methyl 2-chloro-6-methoxy-trans-cinnamate

2,6-dimethoxy-cis-cinnamic acid

methyl 2,6-dimethoxy-cis-cinnamate

Refernces