Technology Process of C27H29N3O2
There total 5 articles about C27H29N3O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane;
at 0 - 20 ℃;
for 12h;
DOI:10.1021/ml400494b
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / dimethyl sulfoxide / 12 h / 130 °C
2: lithium hydroxide monohydrate; water / tetrahydrofuran; methanol / 3 h / 20 °C
3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h / 0 - 20 °C
With
lithium hydroxide monohydrate; water; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/ml400494b
- Guidance literature:
-
Multi-step reaction with 5 steps
1: thionyl chloride / 1 h / 80 °C
2: 0.25 h / 20 °C
3: potassium carbonate / dimethyl sulfoxide / 12 h / 130 °C
4: lithium hydroxide monohydrate; water / tetrahydrofuran; methanol / 3 h / 20 °C
5: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h / 0 - 20 °C
With
thionyl chloride; lithium hydroxide monohydrate; water; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/ml400494b
