2-Propenoic acid, 3-(4-nitrophenyl)-, butyl ester, (2E)-

Base Information

• Chemical Name: 2-Propenoic acid, 3-(4-nitrophenyl)-, butyl ester, (2E)-
• CAS No.: 131061-15-9
• Molecular Formula: C₁₃H₁₅NO₄
• Molecular Weight: 249.266
• Mol file: 131061-15-9.mol

Synonyms:

Chemical Property of 2-Propenoic acid, 3-(4-nitrophenyl)-, butyl ester, (2E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propenoic acid, 3-(4-nitrophenyl)-, butyl ester, (2E)-

There total 35 articles about 2-Propenoic acid, 3-(4-nitrophenyl)-, butyl ester, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + para-nitrophenyl bromide (586-78-7) → (E)-n-butyl 4-nitrocinnamate (86622-84-6,131061-15-9)

Guidance literature:

With tetramethylquanidine; sodium acetate; palladium dichloride; In N,N-dimethyl acetamide; at 140 ℃; for 20h;

DOI:10.1055/s-2005-871581

Reference yield: 100.0%

p-nitrobenzene iodide (636-98-6) + acrylic acid n-butyl ester (141-32-2,9003-49-0) → (E)-n-butyl 4-nitrocinnamate (86622-84-6,131061-15-9)

Guidance literature:

With C₂₉H₃₃Cl₂N₅Pd; tetrabutylammomium bromide; sodium carbonate; In N,N-dimethyl acetamide; at 140 ℃; for 3h; Inert atmosphere;

DOI:10.1021/om100890q

Reference yield: 99.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + 4-chlorobenzonitrile (100-00-5) → (E)-n-butyl 4-nitrocinnamate (86622-84-6,131061-15-9)

Guidance literature:

With tetrabutylammomium bromide; sodium acetate; Pd catalyst; at 150 ℃; for 72h;

DOI:10.1002/(SICI)1521-3765(20000515)6:10<1773::AID-CHEM1773>3.0.CO;2-P

upstream raw materials:

acrylic acid n-butyl ester

4-chlorobenzonitrile

para-nitrophenyl bromide

p-nitrobenzene iodide

Downstream raw materials:

n-butyl 3-[4-(piperazin-1-yl)-phenyl]-propionate

4-nitro-benzoic acid