4-bromo-5-methyl-1H-pyrazole-3-carbohydrazide

Base Information

• Chemical Name: 4-bromo-5-methyl-1H-pyrazole-3-carbohydrazide
• CAS No.: 1043909-04-1
• Molecular Formula: C₅H₇BrN₄O
• Molecular Weight: 219.041
• DSSTox Substance ID: DTXSID20395728
• Wikidata: Q82195957
• Mol file: 1043909-04-1.mol

Synonyms:4-bromo-5-methyl-1H-pyrazole-3-carbohydrazide;1043909-04-1;4-bromo-3-methyl-1H-pyrazole-5-carbohydrazide;DTXSID20395728;MFCD08056670;STK374803;AKOS000276494;AKOS005071119;SB86425;7Z-0829;J-514767

Chemical Property of 4-bromo-5-methyl-1H-pyrazole-3-carbohydrazide

Chemical Property:

• Melting Point: 234-237°
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 217.98032
• Heavy Atom Count: 11
• Complexity: 165

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-5-methyl-1H-pyrazole-3-carbohydrazide >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C(C(=NN1)C(=O)NN)Br

Technology Process of 4-bromo-5-methyl-1H-pyrazole-3-carbohydrazide

There total 4 articles about 4-bromo-5-methyl-1H-pyrazole-3-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester (6076-14-8) → 4-bromo-5-methyl-1(2)H-pyrazole-3-carboxylic acid hydrazide (1043909-04-1)

Guidance literature:

With ethanol; hydrazine hydrate;

Reference yield:

3-methyl-4-nitropyrazole-5-carboxylic acid (5334-38-3) → 4-bromo-5-methyl-1(2)H-pyrazole-3-carboxylic acid hydrazide (1043909-04-1)

Guidance literature:

Multi-step reaction with 4 steps

1: SnCl₂; water; HCl

2: HCl; water; copper-powder; KBr

3: H₂SO₄

4: ethanol; N₂H₄+H₂O

With hydrogenchloride; ethanol; sulfuric acid; water; copper; hydrazine hydrate; tin(ll) chloride; potassium bromide;

Reference yield:

4-amino-5-methyl-1(2)H-pyrazole-3-carboxylic acid (94993-81-4) → 4-bromo-5-methyl-1(2)H-pyrazole-3-carboxylic acid hydrazide (1043909-04-1)

Guidance literature:

Multi-step reaction with 3 steps

1: HCl; water; copper-powder; KBr

2: H₂SO₄

3: ethanol; N₂H₄+H₂O

With hydrogenchloride; ethanol; sulfuric acid; water; copper; hydrazine hydrate; potassium bromide;

upstream raw materials:

4-bromo-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester

3-methyl-4-nitropyrazole-5-carboxylic acid

4-amino-5-methyl-1⁽²⁾H-pyrazole-3-carboxylic acid

4-bromo-5-methyl-1⁽²⁾H-pyrazole-3-carboxylic acid