3(2H)-Pyridazinone, 6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-

Base Information

Chemical Name:3(2H)-Pyridazinone, 6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-
CAS No.:131185-06-3
Molecular Formula:C17H12N4O
Molecular Weight:288.308
Hs Code.:
DSSTox Substance ID:DTXSID00442224
Nikkaji Number:J1.126.043H
Wikidata:Q82259389
ChEMBL ID:CHEMBL166356

Synonyms:131185-06-3;6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)pyridazin-3(2H)-one;3(2H)-Pyridazinone, 6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-;CHEMBL166356;SCHEMBL5810385;DTXSID00442224;MBCUSHSOCQIFLW-UHFFFAOYSA-N;6-(2-Phenylpyrazolo[1,5-a]pyridine-3-yl)pyridazine-3(2H)-one;3- (3-oxo-2, 3-dihydropyridazin-6-yl)-2-phenylpyrazolo[1,5-a]pyridine;3-(3-oxo-2,3-dihydropyridazin-6-yl)-2-phenylpyrazolo[ 1,5-a]pyridine;3-(3-oxo-2,3-dihydropyridazin-6-yl)-2-phenylpyrazolo[1,5-a]pyridine;3-(3-oxo-2,3-dihydropyridazin-6-yl)-2phenylpyrazolo[1,5-a]pyridine;6-{2-phenylpyrazolo[1,5-a]pyridin-3-yl}-2,3-dihydropyridazin-3-one

Suppliers and Price of 3(2H)-Pyridazinone, 6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of 3(2H)-Pyridazinone, 6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:288.10111102
Heavy Atom Count:22
Complexity:495

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NN3C=CC=CC3=C2C4=NNC(=O)C=C4

Technology Process of 3(2H)-Pyridazinone, 6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-

There total 6 articles about 3(2H)-Pyridazinone, 6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: C₁₇H₁₄N₂O₄

: 131185-06-3
3-(3-oxo-2,3-dihydropyridazin-6-yl)-2-phenylpyrazolo<1,5-a>pyridine

Guidance literature:: With hydrazine hydrate; In water; at 105 - 110 ℃; for 2h; Large scale;
DOI:10.1021/op980039c

Reference yield:

: 123-91-1,28347-88-8,28347-91-3,39449-24-6,54841-74-6
1,4-dioxane

: 3-(3-phenylsulfonylpyridazin-6-yl)-2-phenylpyrazolo[1,5-a]pyridine

: 131185-06-3
3-(3-oxo-2,3-dihydropyridazin-6-yl)-2-phenylpyrazolo<1,5-a>pyridine

Guidance literature:: With sodium hydroxide;

Reference yield:

: 1817-57-8
4-phenyl-3-butyne-2-one

: 131185-06-3
3-(3-oxo-2,3-dihydropyridazin-6-yl)-2-phenylpyrazolo<1,5-a>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: potassium hydroxide / dichloromethane; water / 1 h / 5 - 25 °C / Large scale

2: acetic acid / 1,2-dimethoxyethane; ethyl acetate / 6 h / 90 - 95 °C

3: hydrazine hydrate / water / 2 h / 105 - 110 °C / Large scale

With hydrazine hydrate; acetic acid; potassium hydroxide; In 1,2-dimethoxyethane; dichloromethane; water; ethyl acetate; 2: |Aldol Condensation;
DOI:10.1021/op980039c