C₂₂H₂₁N₅O₄S

Base Information

• Chemical Name: C₂₂H₂₁N₅O₄S
• CAS No.: 1357853-58-7
• Molecular Formula: C₂₂H₂₁N₅O₄S
• Molecular Weight: 451.506
• Mol file: 1357853-58-7.mol

Synonyms:

Chemical Property of C₂₂H₂₁N₅O₄S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₁N₅O₄S

There total 2 articles about C₂₂H₂₁N₅O₄S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

morpholine (110-91-8,99108-56-2) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + C17H12N4O3S (1357853-74-7) → C22H21N5O4S (1357853-58-7)

Guidance literature:

With acetic acid; In methanol; for 8h; Reflux;

DOI:10.1002/jhet.678

Reference yield:

α-bromoacetophenone (70-11-1) + 5-[(4-nitrophenoxy)methyl]-1,3,4-thiadiazol-2-amine (331818-28-1) → C22H21N5O4S (1357853-58-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / Microwave irradiation

2: acetic acid / methanol / 8 h / Reflux

With acetic acid; In methanol; ethanol; 2: Mannich reaction;

DOI:10.1002/jhet.678

upstream raw materials:

morpholine

formaldehyd

C₁₇H₁₂N₄O₃S

α-bromoacetophenone

Refernces