8H-Indeno[2,1-b]thiophen-8-one

Base Information

Chemical Name:8H-Indeno[2,1-b]thiophen-8-one
CAS No.:13132-12-2
Molecular Formula:C11H6OS
Molecular Weight:186.234
Hs Code.:
DSSTox Substance ID:DTXSID00512072
Nikkaji Number:J1.791.882F
Wikidata:Q82371160

Synonyms:8H-Indeno[2,1-b]thiophen-8-one;13132-12-2;indeno[2,1-b]thiophen-8-one;SCHEMBL7318972;DTXSID00512072;FFQQXIVOSCLQKP-UHFFFAOYSA-N

Suppliers and Price of 8H-Indeno[2,1-b]thiophen-8-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 8H-Indeno[2,1-b]thiophen-8-one

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:186.01393598
Heavy Atom Count:13
Complexity:238

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C3=C(C2=O)SC=C3

Technology Process of 8H-Indeno[2,1-b]thiophen-8-one

There total 3 articles about 8H-Indeno[2,1-b]thiophen-8-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 1438251-52-5
(3-chlorothiophen-2-yl)(phenyl)methanone

: 135-00-2
2-Benzoylthiophene

: 13132-12-2
8H-Indeno<2,1-b>thiophen-8-one

Guidance literature:: With palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate; In N,N-dimethyl-formamide; at 130 ℃; for 24h; Reagent/catalyst; Schlenk technique; Inert atmosphere;
DOI:10.1016/j.tet.2013.09.030

Reference yield:

: 930-96-1
3-bromo-2-thiophenecarboxaldehyde

: 583-55-1
1-Bromo-2-iodobenzene

: 13132-12-2
8H-Indeno<2,1-b>thiophen-8-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: TurboGrignard / tetrahydrofuran / 2 h / -15 °C

1.2: 0.5 h / -15 °C

2.1: palladium diacetate; caesium carbonate; tetra-(n-butyl)ammonium iodide / toluene / 16 h / 110 °C / Inert atmosphere

With TurboGrignard; palladium diacetate; tetra-(n-butyl)ammonium iodide; caesium carbonate; In tetrahydrofuran; toluene;
DOI:10.1039/c7ob02895d