1-Benzyl 3-methyl 1H-indole-1,3-dicarboxylate

Base Information

Chemical Name:1-Benzyl 3-methyl 1H-indole-1,3-dicarboxylate
CAS No.:131424-24-3
Molecular Formula:C₁₈H₁₅NO₄
Molecular Weight:309.321
Hs Code.:
DSSTox Substance ID:DTXSID60564032
Wikidata:Q82448601

Synonyms:131424-24-3;1-Benzyl 3-methyl 1H-indole-1,3-dicarboxylate;SCHEMBL7166450;DTXSID60564032

Suppliers and Price of 1-Benzyl 3-methyl 1H-indole-1,3-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Benzyl 3-methyl 1H-indole-1,3-dicarboxylate

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:309.10010796
Heavy Atom Count:23
Complexity:433

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CN(C2=CC=CC=C21)C(=O)OCC3=CC=CC=C3

Technology Process of 1-Benzyl 3-methyl 1H-indole-1,3-dicarboxylate

There total 1 articles about 1-Benzyl 3-methyl 1H-indole-1,3-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 6092-74-6
N-benzoyloxycarbonylphenylhydroxylamine

: 922-67-8
propynoic acid methyl ester

: 131424-24-3
methyl 1-carbobenzyloxyindole-3-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In nitromethane; Product distribution; Mechanism; Ambient temperature; various bases and solvents; other subst. of N-phenylbenzohydroxamic acid;

Reference yield:

: 131424-24-3
methyl 1-carbobenzyloxyindole-3-carboxylate

: 73183-34-3
bis(pinacol)diborane

: C₂₄H₂₈BNO₆

: C₂₄H₂₈BNO₆

Guidance literature:: With (R,R)-(?)-2,3-bis(t-butylmethylphosphino)quinoxaline; sodium methylate; copper(l) chloride; tert-butyl alcohol; In toluene; at 0 ℃; for 18h; Overall yield = 76 %; stereoselective reaction;
DOI:10.1039/c8sc01815d