Technology Process of Acetic acid 1-[2-(4-methoxy-phenyl)-ethyl]-5-(2,3,4-trimethoxy-phenyl)-pentyl ester
There total 9 articles about Acetic acid 1-[2-(4-methoxy-phenyl)-ethyl]-5-(2,3,4-trimethoxy-phenyl)-pentyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 1.) aluminium chloride, 2.) sodium dithionite, sodium hydroxide / 1.) 1,1,2,2-tetrachloroethane, room temperature, 16 h; steam-bath, 2 h, 2.) methanol, room temperature, 21 h, reflux, 24 h
2: 88 percent / hydrogen / palladium-carbon / acetic acid / 1.5 h / Ambient temperature
3: 59 percent / lithium aluminium hydride / diethyl ether
4: 62 percent / pyridine
5: 80 percent / lithium bromide / acetone / 24 h / Ambient temperature
6: 16 percent / magnesium (from magnesium chloride and potassium metal) / tetrahydrofuran
7: pyridine
With
pyridine; sodium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; sodium dithionite; hydrogen; magnesium; lithium bromide;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; acetic acid; acetone;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 88 percent / hydrogen / palladium-carbon / acetic acid / 1.5 h / Ambient temperature
2: 59 percent / lithium aluminium hydride / diethyl ether
3: 62 percent / pyridine
4: 80 percent / lithium bromide / acetone / 24 h / Ambient temperature
5: 16 percent / magnesium (from magnesium chloride and potassium metal) / tetrahydrofuran
6: pyridine
With
pyridine; lithium aluminium tetrahydride; hydrogen; magnesium; lithium bromide;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; acetic acid; acetone;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 59 percent / lithium aluminium hydride / diethyl ether
2: 62 percent / pyridine
3: 80 percent / lithium bromide / acetone / 24 h / Ambient temperature
4: 16 percent / magnesium (from magnesium chloride and potassium metal) / tetrahydrofuran
5: pyridine
With
pyridine; lithium aluminium tetrahydride; magnesium; lithium bromide;
In
tetrahydrofuran; diethyl ether; acetone;
