N-(4'-Hydroxy(1,1'-biphenyl)-4-yl)acetamide

Base Information

Chemical Name:N-(4'-Hydroxy(1,1'-biphenyl)-4-yl)acetamide
CAS No.:13171-43-2
Molecular Formula:C₁₄H₁₃NO₂
Molecular Weight:227.263
Hs Code.:2924299090
DSSTox Substance ID:DTXSID60927325
Nikkaji Number:J381.160C
Wikidata:Q82901946
Mol file:13171-43-2.mol

Synonyms:13171-43-2;N-(4'-Hydroxy(1,1'-biphenyl)-4-yl)acetamide;N-[4-(4-hydroxyphenyl)phenyl]acetamide;Acetamide, N-(4'-hydroxy(1,1'-biphenyl)-4-yl)-;N-(4/'-Hydroxy(1,1/'-biphenyl)-4-yl)acetamide;4'-hydroxy-4-acetamidobiphenyl;SCHEMBL2605857;DTXSID60927325;AKOS005145201;N-(4'-Hydroxy[1,1'-biphenyl]-4-yl)ethanimidic acid;Z2183700127

Suppliers and Price of N-(4'-Hydroxy(1,1'-biphenyl)-4-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-(4'-HYDROXY(1,1'-BIPHENYL)-4-YL)ACETAMIDE 95.00%
5MG
$ 505.38

Total 5 raw suppliers

Chemical Property of N-(4'-Hydroxy(1,1'-biphenyl)-4-yl)acetamide

Chemical Property:

PSA：52.82000
LogP:3.66710
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:227.094628657
Heavy Atom Count:17
Complexity:251

Purity/Quality:

99% ^*data from raw suppliers

N-(4'-HYDROXY(1,1'-BIPHENYL)-4-YL)ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)C2=CC=C(C=C2)O

Technology Process of N-(4'-Hydroxy(1,1'-biphenyl)-4-yl)acetamide

There total 7 articles about N-(4'-Hydroxy(1,1'-biphenyl)-4-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 1204-79-1
4-amino-4'-hydroxybiphenyl

: 75-36-5
acetyl chloride

: 13171-43-2
4'-hydroxy-4-acetylaminobiphenyl

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 12h;
DOI:10.1021/ja038016n

Reference yield:

: 3916-44-7
4-(4-nitrophenyl)phenol

: 13171-43-2
4'-hydroxy-4-acetylaminobiphenyl

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / H₂ / Pd/C / ethyl acetate / 18 h / 20 °C / 1861.73 Torr

2: 58 percent / DIEA / tetrahydrofuran / 12 h / 20 °C

With hydrogen; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate;
DOI:10.1021/ja038016n