Ph₂PCH₂NHC₆H₄(4-COOH)

Base Information

• Chemical Name: Ph₂PCH₂NHC₆H₄(4-COOH)
• CAS No.: 434315-17-0
• Molecular Formula: C₂₀H₁₈NO₂P
• Molecular Weight: 335.342
• Mol file: 434315-17-0.mol

Synonyms:

Chemical Property of Ph₂PCH₂NHC₆H₄(4-COOH)

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Ph₂PCH₂NHC₆H₄(4-COOH)

There total 1 articles about Ph₂PCH₂NHC₆H₄(4-COOH) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) + diphenylphosphinomethanol (5958-44-1) → Ph2PCH2NHC6H4(4-COOH) (434315-17-0)

Guidance literature:

In methanol; at 20 ℃;

DOI:10.1016/S0040-4039(01)02361-9

Reference yield: 93.0%

[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 (52462-29-0) + dichloromethane (75-09-2) + Ph2PCH2NHC6H4(4-COOH) (434315-17-0) → [RuCl2(p-cymene)(PPh2CH2NHC6H4(4-COOH))]*0.5CH2Cl2

Guidance literature:

In dichloromethane; addn. of Ph2PCH2NHC6H4(4-COOH) (2 equiv.) to CH2Cl2 soln. of (RuCl2(p-cymene))2 (1 equiv.) in CH2Cl2 at room temp.; stirring for 15 min; concn. under reduced pressure, addn. of Et2O; filtration, drying in vac.elem. anal.;

DOI:10.1016/j.jorganchem.2006.07.036

upstream raw materials:

4-amino-benzoic acid

diphenylphosphinomethanol