methyl (2S)-2-amino-3-cyclopropylpropanoate

Base Information

Chemical Name:methyl (2S)-2-amino-3-cyclopropylpropanoate
CAS No.:732231-41-3
Molecular Formula:C₇H₁₃NO₂
Molecular Weight:143.186
Hs Code.:
European Community (EC) Number:845-144-2

Synonyms:732231-41-3;methyl (2S)-2-amino-3-cyclopropylpropanoate;SCHEMBL75595;(S)-Methyl2-amino-3-cyclopropylpropanoate;(S)-Methyl 2-amino-3-cyclopropylpropanoate;EN300-1068711

Suppliers and Price of methyl (2S)-2-amino-3-cyclopropylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
Methyl(2S)-2-amino-3-cyclopropylpropanoate
2.5g
$ 683.00

Total 0 raw suppliers

Chemical Property of methyl (2S)-2-amino-3-cyclopropylpropanoate

Chemical Property:

Boiling Point:184.4±13.0 °C(Predicted)
Density:1.089±0.06 g/cm3(Predicted)
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:143.094628657
Heavy Atom Count:10
Complexity:132

Purity/Quality:: Methyl(2S)-2-amino-3-cyclopropylpropanoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C(CC1CC1)N
Isomeric SMILES:COC(=O)[C@H](CC1CC1)N

Technology Process of methyl (2S)-2-amino-3-cyclopropylpropanoate

There total 1 articles about methyl (2S)-2-amino-3-cyclopropylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 102735-53-5,15785-52-1
(2S)-2-amino-3-cyclopropylpropanoic acid

: 732231-41-3,1251904-24-1
methyl (S)-2-amino-3-cyclopropylpropanoate

Guidance literature:: With thionyl chloride; at 0 ℃; for 16h; Inert atmosphere; Reflux;

Reference yield: 67.0%

: 732231-41-3,1251904-24-1
methyl (S)-2-amino-3-cyclopropylpropanoate

: 24424-99-5
di-tert-butyl dicarbonate

: 104347-84-4
methyl (S)-2-((tert-butoxycarbonyl)amino)-3-cyclopropylpropanoate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 16h; Inert atmosphere;

Reference yield:

: 732231-41-3,1251904-24-1
methyl (S)-2-amino-3-cyclopropylpropanoate

: (S)-2-((2-chloro-5-((4-methoxybenzyl)oxy)pyrimidin-4-yl)(methyl)amino)-3-cyclopropylpropan-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere

2: lithium aluminium tetrahydride / tetrahydrofuran / 16 h / 0 - 80 °C / Inert atmosphere

3: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / tetrahydrofuran / 3 h / 80 °C / Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; lithium aluminium tetrahydride; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triethylamine; In tetrahydrofuran; dichloromethane;