n-(4-Amino-2-fluorophenyl)acetamide

Base Information

Chemical Name:n-(4-Amino-2-fluorophenyl)acetamide
CAS No.:57165-12-5
Molecular Formula:C8H9 F N2 O
Molecular Weight:168.1683
Hs Code.:
European Community (EC) Number:848-693-6
NSC Number:81336
DSSTox Substance ID:DTXSID30972625
Wikidata:Q82956415

Synonyms:n-(4-amino-2-fluorophenyl)acetamide;57165-12-5;1-amino-4-acetylamino-3-fluorobenzene;NSC81336;NCIOpen2_000952;SCHEMBL116618;DTXSID30972625;URXXVRGEJLUCNC-UHFFFAOYSA-N;NSC-81336;STL411822;AKOS000298885;BS-38328;N-(4-Amino-2-fluorophenyl)ethanimidic acid;CS-0117949

Suppliers and Price of n-(4-Amino-2-fluorophenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(4-amino-2-fluorophenyl)acetamideHydrochloridehydrate
100mg
$ 60.00

ChemBridge Corporation
N-(4-amino-2-fluorophenyl)acetamidehydrochloridehydrate 95%
1 g
$ 98.00

American Custom Chemicals Corporation
N-(4-AMINO-2-FLUOROPHENYL)ACETAMIDE 95.00%
5MG
$ 499.99

Total 8 raw suppliers

Chemical Property of n-(4-Amino-2-fluorophenyl)acetamide

Chemical Property:

Vapor Pressure:0.0147mmHg at 25°C
Boiling Point:257.2°C at 760 mmHg
Flash Point:109.4°C
PSA：55.12000
Density:1.303g/cm³
LogP:2.02050
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:168.06989108
Heavy Atom Count:12
Complexity:174

Purity/Quality:

99% ^*data from raw suppliers

N-(4-amino-2-fluorophenyl)acetamideHydrochloridehydrate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=C(C=C(C=C1)N)F

Technology Process of n-(4-Amino-2-fluorophenyl)acetamide

There total 4 articles about n-(4-Amino-2-fluorophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 348-19-6
2'-fluoro-4'-nitroacetanilide

: 57165-12-5
4-amino-2-fluoroacetanilide

Guidance literature:: With palladium hydroxide 10 wt. % on activated carbon; hydrogen; at 20 ℃; for 12h; under 750.075 Torr; Inert atmosphere;
DOI:10.1002/ejoc.201500795

Reference yield:

: 369-35-7
2-fluoro-4-nitroaniline

: 57165-12-5
4-amino-2-fluoroacetanilide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium acetate / tetrahydrofuran / 12 h / 0 - 20 °C / Inert atmosphere

2: palladium hydroxide 10 wt. % on activated carbon; hydrogen / 12 h / 20 °C / 750.08 Torr / Inert atmosphere

With palladium hydroxide 10 wt. % on activated carbon; hydrogen; sodium acetate; In tetrahydrofuran;
DOI:10.1002/ejoc.201500795