(2-Chloro-8-methoxy-3-quinolinyl)-boronic acid

Base Information

Chemical Name:(2-Chloro-8-methoxy-3-quinolinyl)-boronic acid
CAS No.:220506-64-9
Molecular Formula:C₁₀H₉BClNO₃
Molecular Weight:237.45
Hs Code.:
DSSTox Substance ID:DTXSID00453517
Wikidata:Q82274671

Synonyms:220506-64-9;(2-CHLORO-8-METHOXY-3-QUINOLINYL)-BORONIC ACID;(2-chloro-8-methoxyquinolin-3-yl)boronic acid;AGN-PC-0NF41F;DTXSID00453517

Suppliers and Price of (2-Chloro-8-methoxy-3-quinolinyl)-boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
(2-chloro-8-methoxy-3-quinolinyl)-Boronicacid 97.00%
25G
$ 9110.00

AccelPharmtech
(2-chloro-8-methoxy-3-quinolinyl)-Boronicacid 97.00%
5G
$ 4850.00

AccelPharmtech
(2-chloro-8-methoxy-3-quinolinyl)-Boronicacid 97.00%
1G
$ 2820.00

Total 1 raw suppliers

Chemical Property of (2-Chloro-8-methoxy-3-quinolinyl)-boronic acid

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:237.0364010
Heavy Atom Count:16
Complexity:244

Purity/Quality:

95%-98% ^*data from raw suppliers

(2-chloro-8-methoxy-3-quinolinyl)-Boronicacid 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B(C1=CC2=C(C(=CC=C2)OC)N=C1Cl)(O)O

Technology Process of (2-Chloro-8-methoxy-3-quinolinyl)-boronic acid

There total 5 articles about (2-Chloro-8-methoxy-3-quinolinyl)-boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 74668-74-9
2-chloro-8-methoxy-quinoline

: 220506-64-9
(2-CHLORO-8-METHOXY-3-QUINOLINYL)-BORONIC ACID

Guidance literature:: With Trimethyl borate; 2,2,6,6-tetramethylpiperidinyl-lithium; In tetrahydrofuran; at -75 ℃; for 2h;
DOI:10.3987/com-98-8326

Reference yield:

: 22614-69-3
8-methoxy-1H-quinolin-2-one

: 220506-64-9
(2-CHLORO-8-METHOXY-3-QUINOLINYL)-BORONIC ACID

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / phosphorus oxychloride, pyridine / chlorobenzene / 2 h / Heating

2: 82 percent / lithium tetramethylpiperidide, trimethyl borate / tetrahydrofuran / 2 h / -75 °C

With pyridine; Trimethyl borate; 2,2,6,6-tetramethylpiperidinyl-lithium; trichlorophosphate; In tetrahydrofuran; chlorobenzene;
DOI:10.3987/com-98-8326

Reference yield:

: 126582-57-8
(E)-N-(2-methoxyphenyl)-3-phenylacrylamide

: 220506-64-9
(2-CHLORO-8-METHOXY-3-QUINOLINYL)-BORONIC ACID

Guidance literature:: Multi-step reaction with 4 steps

1: AlCl₃ / chlorobenzene

2: 95 percent / potassium carbonate / acetone / 2 h / Heating

3: 99 percent / phosphorus oxychloride, pyridine / chlorobenzene / 2 h / Heating

4: 82 percent / lithium tetramethylpiperidide, trimethyl borate / tetrahydrofuran / 2 h / -75 °C

With pyridine; aluminium trichloride; Trimethyl borate; 2,2,6,6-tetramethylpiperidinyl-lithium; potassium carbonate; trichlorophosphate; In tetrahydrofuran; chlorobenzene; acetone;
DOI:10.3987/com-98-8326