(R)-(+)-3-Propylcyclohexanone

Base Information

• Chemical Name: (R)-(+)-3-Propylcyclohexanone
• CAS No.: 73959-35-0
• Molecular Formula: C₉H₁₆O
• Molecular Weight: 140.225
• Mol file: 73959-35-0.mol

Synonyms:

Chemical Property of (R)-(+)-3-Propylcyclohexanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-(+)-3-Propylcyclohexanone

There total 5 articles about (R)-(+)-3-Propylcyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Oxo-6-((E)-propenyl)-cyclohexanecarboxylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester → (R)-(+)-3-Propylcyclohexanone (73959-35-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / H₂ / 10percent Pd/C / CH₂Cl₂ / 2 h / 25 °C / 760 Torr

2: NaCl / dimethylsulfoxide; H₂O / 20 h / Heating

With hydrogen; sodium chloride; palladium on activated charcoal; In dichloromethane; water; dimethyl sulfoxide;

DOI:10.1021/jo00079a006

Reference yield:

3-propyl-2-cyclohexen-1-one (6328-24-1) → (R)-(+)-3-Propylcyclohexanone (73959-35-0) + (S)-(-)-3-Propylcyclohexanone (73959-34-9)

Guidance literature:

With (S)-(+)-5,5’-bis[di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-4,4’-bi-1,3-benzodioxole; bis(cycloocta-1,5-diene)rhodium(I) trifluoromethanesulfonate; hydrogen; [1,1'-(butane-1,4-diyl)bis(triphenylphosphonium)] dibromide; In ethyl acetate; at 50 ℃; for 3h; under 22067.3 Torr; Autoclave;

DOI:10.1002/chem.200701505

Reference yield:

2-Oxo-6-propyl-cyclohexanecarboxylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester → (R)-(+)-3-Propylcyclohexanone (73959-35-0) + (S)-(-)-3-Propylcyclohexanone (73959-34-9)

Guidance literature:

With sodium chloride; In water; dimethyl sulfoxide; for 20h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;

DOI:10.1021/jo00079a006

upstream raw materials:

3-n-propylcyclohexanone

cyclohexenone

1-propylmagnesium chloride

3-propyl-2-cyclohexen-1-one