[(S)-1-((Z)-2-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-{(E)-2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinylcarbamoyl}-vinylcarbamoyl)-3-methyl-butyl]-carbamic acid tert-butyl ester

Base Information

• Chemical Name: [(S)-1-((Z)-2-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-{(E)-2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinylcarbamoyl}-vinylcarbamoyl)-3-methyl-butyl]-carbamic acid tert-butyl ester
• CAS No.: 132245-89-7
• Molecular Formula: C₅₂H₉₁N₃O₈Si₄
• Molecular Weight: 998.652

Synonyms:

Chemical Property of [(S)-1-((Z)-2-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-{(E)-2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinylcarbamoyl}-vinylcarbamoyl)-3-methyl-butyl]-carbamic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(S)-1-((Z)-2-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-{(E)-2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinylcarbamoyl}-vinylcarbamoyl)-3-methyl-butyl]-carbamic acid tert-butyl ester

There total 26 articles about [(S)-1-((Z)-2-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-{(E)-2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinylcarbamoyl}-vinylcarbamoyl)-3-methyl-butyl]-carbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) → [(S)-1-((E)-2-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-{(E)-2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinylcarbamoyl}-vinylcarbamoyl)-3-methyl-butyl]-carbamic acid tert-butyl ester (132245-89-7,132340-62-6)

Guidance literature:

Multi-step reaction with 11 steps

1: 98 percent / imidazole / CH₂Cl₂

2: 100 percent / ZnI₂

3: LiAlH₄ / tetrahydrofuran

4: CH₂Cl₂

5: 75 percent / n-Bu₃P / tetrahydrofuran

6: 100 percent / 30percent TFA / CH₂Cl₂

7: 85 percent / DCC / CH₂Cl₂

8: 78 percent / H₂O₂, pyridine / tetrahydrofuran

9: 100 percent / TFA / CH₂Cl₂

10: 75 percent

11: 1) LDA / 1) THF 2) hν, hexane

With pyridine; 1H-imidazole; lithium aluminium tetrahydride; tributylphosphine; dihydrogen peroxide; dicyclohexyl-carbodiimide; trifluoroacetic acid; zinc(II) iodide; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0040-4039(00)97256-3

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) → [(S)-1-((Z)-2-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-{(E)-2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinylcarbamoyl}-vinylcarbamoyl)-3-methyl-butyl]-carbamic acid tert-butyl ester (132245-89-7,132340-62-6)

Guidance literature:

Multi-step reaction with 11 steps

1: 98 percent / imidazole / CH₂Cl₂

2: 100 percent / ZnI₂

3: LiAlH₄ / tetrahydrofuran

4: CH₂Cl₂

5: 75 percent / n-Bu₃P / tetrahydrofuran

6: 100 percent / 30percent TFA / CH₂Cl₂

7: 85 percent / DCC / CH₂Cl₂

8: 78 percent / H₂O₂, pyridine / tetrahydrofuran

9: 100 percent / TFA / CH₂Cl₂

10: 75 percent

11: 1) LDA / 1) THF 2) hν, hexane

With pyridine; 1H-imidazole; lithium aluminium tetrahydride; tributylphosphine; dihydrogen peroxide; dicyclohexyl-carbodiimide; trifluoroacetic acid; zinc(II) iodide; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0040-4039(00)97256-3

Reference yield:

3,4-dihydroxybenzaldehyde (139-85-5) → [(S)-1-((E)-2-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-{(E)-2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinylcarbamoyl}-vinylcarbamoyl)-3-methyl-butyl]-carbamic acid tert-butyl ester (132245-89-7,132340-62-6)

Guidance literature:

Multi-step reaction with 11 steps

1: 98 percent / imidazole / CH₂Cl₂

2: 100 percent / ZnI₂

3: LiAlH₄ / tetrahydrofuran

4: CH₂Cl₂

5: 75 percent / n-Bu₃P / tetrahydrofuran

6: 100 percent / 30percent TFA / CH₂Cl₂

7: 85 percent / DCC / CH₂Cl₂

8: 78 percent / H₂O₂, pyridine / tetrahydrofuran

9: 100 percent / TFA / CH₂Cl₂

10: 75 percent

11: 1) LDA / 1) THF 2) hν, hexane

With pyridine; 1H-imidazole; lithium aluminium tetrahydride; tributylphosphine; dihydrogen peroxide; dicyclohexyl-carbodiimide; trifluoroacetic acid; zinc(II) iodide; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0040-4039(00)97256-3

upstream raw materials:

3,4-bis(tert-butyldimethylsilanyloxy)benzaldehyde

[{(E)-2-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinylcarbamoyl}-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-methyl]-phosphonic acid dimethyl ester

N-tert-butoxycarbonyl-L-leucine

2-Amino-1-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-ethanol

Downstream raw materials:

Tunichrome Mm-2

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 132245-89-7 [(S)-1-((Z)-2-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-{(E)-2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-vinylcarbamoyl}-vinylcarbamoyl)-3-methyl-butyl]-carbamic acid tert-butyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send