Technology Process of Methyl-4,6-O-benzyliden-3-<(benzyloxycarbonyl)amino>-2-O-methyl-3-desoxy-α-D-erythro-hex-2-enopyranosid
There total 10 articles about Methyl-4,6-O-benzyliden-3-<(benzyloxycarbonyl)amino>-2-O-methyl-3-desoxy-α-D-erythro-hex-2-enopyranosid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 5 steps
1: 68 percent / LiN3 / dimethylsulfoxide; dimethylformamide / 4.5 h / 50 °C
2: 1.) 1percent NaOMe; 2.) H2 / 2.) 10percent Pd/C / 1.) CH3OH, 4 h, r.t.; 2.) CH3OH, 18 h
3: 85 percent / NaHCO3 / H2O; acetone / 0.5 h / 0 °C
4: 990 mg / oxalylchloride, DMSO, / CH2Cl2 / 0.25 h / -25 °C
5: 1.) LDA; 2.) CH3I / 1.) THF, -78 degC, 60 min; 2.) HMPA, r.t., 2 h
With
lithium azide; Chloro-oxo-acetic acid; hydrogen; sodium methylate; sodium hydrogencarbonate; dimethyl sulfoxide; lithium diisopropyl amide; methyl iodide;
palladium on activated charcoal;
In
dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone;
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28642-64-0,35823-97-3,38992-99-3,51591-23-2,55169-75-0,56253-26-0,72659-78-0,80041-30-1,80299-59-8,86420-70-4,86420-72-6,91685-06-2,99265-94-8,109010-33-5,118246-05-2,126255-07-0
methyl 2-O-benzoyl-4,6-di-O-benzylidene-α-D-glucopyranoside
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 92 percent / CH2Cl2; pyridine / 5 h / Ambient temperature
2: 68 percent / LiN3 / dimethylsulfoxide; dimethylformamide / 4.5 h / 50 °C
3: 1.) 1percent NaOMe; 2.) H2 / 2.) 10percent Pd/C / 1.) CH3OH, 4 h, r.t.; 2.) CH3OH, 18 h
4: 85 percent / NaHCO3 / H2O; acetone / 0.5 h / 0 °C
5: 990 mg / oxalylchloride, DMSO, / CH2Cl2 / 0.25 h / -25 °C
6: 1.) LDA; 2.) CH3I / 1.) THF, -78 degC, 60 min; 2.) HMPA, r.t., 2 h
With
lithium azide; Chloro-oxo-acetic acid; hydrogen; sodium methylate; sodium hydrogencarbonate; dimethyl sulfoxide; lithium diisopropyl amide; methyl iodide;
palladium on activated charcoal;
In
pyridine; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) 1percent NaOMe; 2.) H2 / 2.) 10percent Pd/C / 1.) CH3OH, 4 h, r.t.; 2.) CH3OH, 18 h
2: 85 percent / NaHCO3 / H2O; acetone / 0.5 h / 0 °C
3: 990 mg / oxalylchloride, DMSO, / CH2Cl2 / 0.25 h / -25 °C
4: 1.) LDA; 2.) CH3I / 1.) THF, -78 degC, 60 min; 2.) HMPA, r.t., 2 h
With
Chloro-oxo-acetic acid; hydrogen; sodium methylate; sodium hydrogencarbonate; dimethyl sulfoxide; lithium diisopropyl amide; methyl iodide;
palladium on activated charcoal;
In
dichloromethane; water; acetone;
