N^α-Benzyloxycarbonyl-N^ε-nitro-L-arginyl-L-alanin

Base Information

• Chemical Name: N^α-Benzyloxycarbonyl-N^ε-nitro-L-arginyl-L-alanin
• CAS No.: 106571-84-0
• Molecular Formula: C₁₇H₂₄N₆O₇
• Molecular Weight: 424.414
• Mol file: 106571-84-0.mol

Synonyms:

Chemical Property of N^α-Benzyloxycarbonyl-N^ε-nitro-L-arginyl-L-alanin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^α-Benzyloxycarbonyl-N^ε-nitro-L-arginyl-L-alanin

There total 6 articles about N^α-Benzyloxycarbonyl-N^ε-nitro-L-arginyl-L-alanin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(Nα-benzyloxycarbonyl-Nω-nitro-L-arginyl)-L-alanine methyl ester (13850-69-6) → N-(Nα-benzyloxycarbonyl-Nω-nitro-L-arginyl)-L-alanine (106571-84-0)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01582a065

Reference yield:

N5-[imino(nitroamino)methyl]-N2-[(phenylmethoxy)carbonyl]-L-ornithine (2304-98-5) → N-(Nα-benzyloxycarbonyl-Nω-nitro-L-arginyl)-L-alanine (106571-84-0)

Guidance literature:

Multi-step reaction with 2 steps

1: tributylamine; chlorocarbonic acid ethyl ester; dioxane / anschliessend Behandeln mit L-Alanin-methylester

2: aqueous NaOH

With 1,4-dioxane; sodium hydroxide; tributyl-amine; chloroformic acid ethyl ester;

DOI:10.1021/ja01582a065

Reference yield:

N-nitro-L-arginine (2149-70-4,13855-78-2,38733-00-5) → N-(Nα-benzyloxycarbonyl-Nω-nitro-L-arginyl)-L-alanine (106571-84-0)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. NaOH

2: (i) Et₃N, ClCO₂Et, THF, (ii) /BRN= 1720585/

3: aq. NaOH / acetone

With sodium hydroxide; In acetone;

upstream raw materials:

N-(N^α-benzyloxycarbonyl-N^ω-nitro-L-arginyl)-L-alanine methyl ester

N₅-[imino(nitroamino)methyl]-N₂-[(phenylmethoxy)carbonyl]-L-ornithine

N-nitro-L-arginine

N^ω-nitro-L-arginine

Downstream raw materials:

Arg-Ala