4-[(2-Butyl-1H-benzimidazol-1-yl)methyl]benzoic acid

Base Information

Chemical Name:4-[(2-Butyl-1H-benzimidazol-1-yl)methyl]benzoic acid
CAS No.:133052-85-4
Molecular Formula:C19H20N2O2
Molecular Weight:308.38
Hs Code.:
ChEMBL ID:CHEMBL171456
DSSTox Substance ID:DTXSID80566593
Nikkaji Number:J467.441C
Wikidata:Q82452273

Synonyms:4-[(2-Butyl-1H-benzimidazol-1-yl)methyl]benzoic acid;133052-85-4;4-[(2-butylbenzimidazol-1-yl)methyl]benzoic acid;CHEMBL171456;SCHEMBL9123025;DTXSID80566593;AYUAYHAZNQPDLH-UHFFFAOYSA-N;BDBM50230431;EN300-7529847;L006146;Z54584204;4-[(2-butyl-1H-1,3-benzodiazol-1-yl)methyl]benzoic acid

Suppliers and Price of 4-[(2-Butyl-1H-benzimidazol-1-yl)methyl]benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-[(2-Butyl-1H-benzimidazol-1-yl)methyl]benzoic acid

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:308.152477885
Heavy Atom Count:23
Complexity:393

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC1=NC2=CC=CC=C2N1CC3=CC=C(C=C3)C(=O)O

Technology Process of 4-[(2-Butyl-1H-benzimidazol-1-yl)methyl]benzoic acid

There total 5 articles about 4-[(2-Butyl-1H-benzimidazol-1-yl)methyl]benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 138459-22-0
2-butyl-1-<(4-cyanophenyl)methyl>benzimidazole

: 133052-85-4
4-[(2-butyl-1H-benzimidazol-1-yl)-methyl]-benzoic acid

Guidance literature:: In ethyl acetate;

Reference yield:

: 133052-51-4
methyl 4'-[(2-butyl-1H-benzimidazol-1-yl)methyl]benzoate

: 133052-85-4
4-[(2-butyl-1H-benzimidazol-1-yl)-methyl]-benzoic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 3h; Heating;
DOI:10.1021/jm00083a011

Reference yield:

: 5851-44-5
2-n-butylbenzimidazole

: 133052-85-4
4-[(2-butyl-1H-benzimidazol-1-yl)-methyl]-benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dimethylformamide / 3 h / 100 °C

2: aq. NaOH / ethanol / 3 h / Heating

With sodium hydroxide; potassium carbonate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00083a011