Technology Process of 3-(2-o-methoxyphenylethylidene)isoindolinone
There total 4 articles about 3-(2-o-methoxyphenylethylidene)isoindolinone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
tetrahydrofuran;
for 0.5h;
Yield given;
Ambient temperature;
DOI:10.1248/cpb.41.2003
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 75 percent / thionyl chloride / benzene / 2 h / 50 °C
2: 1.) Mg / 1.) THF, 50 deg C, 1 h, 2.) THF, RT, 8 h
3: 15percent aq. HCl / tetrahydrofuran / 0.5 h / Ambient temperature
With
hydrogenchloride; thionyl chloride; magnesium;
In
tetrahydrofuran; benzene;
DOI:10.1248/cpb.41.2003
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 87 percent / lithium aluminum hydride / diethyl ether / 0.5 h / Heating
2: 75 percent / thionyl chloride / benzene / 2 h / 50 °C
3: 1.) Mg / 1.) THF, 50 deg C, 1 h, 2.) THF, RT, 8 h
4: 15percent aq. HCl / tetrahydrofuran / 0.5 h / Ambient temperature
With
hydrogenchloride; lithium aluminium tetrahydride; thionyl chloride; magnesium;
In
tetrahydrofuran; diethyl ether; benzene;
DOI:10.1248/cpb.41.2003