Technology Process of C27H42N4O5
There total 5 articles about C27H42N4O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C18H29N5O3*ClH;
With
hydrogenchloride; tert.-butylnitrite;
In
1,4-dioxane; ethyl acetate; N,N-dimethyl-formamide;
at -30 ℃;
for 3h;
Inert atmosphere;
(S)-2-amino-4-methyl-1-((R)-2-methyloxiran-2-yl)pentan-1-one trifluoroacetic acid salt;
With
N-ethyl-N,N-diisopropylamine;
In
1,4-dioxane; ethyl acetate; N,N-dimethyl-formamide;
at -30 - 20 ℃;
Inert atmosphere;
DOI:10.1039/c1ob06554h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / Inert atmosphere
2.1: hydrogenchloride / 1,4-dioxane / 1 h / Inert atmosphere
3.1: hydrogenchloride; tert.-butylnitrite / 1,4-dioxane; ethyl acetate; N,N-dimethyl-formamide / 3 h / -30 °C / Inert atmosphere
3.2: -30 - 20 °C / Inert atmosphere
With
hydrogenchloride; tert.-butylnitrite; N-ethyl-N,N-diisopropylamine;
In
1,4-dioxane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1039/c1ob06554h
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrogenchloride / 1,4-dioxane / 1 h / Inert atmosphere
2.1: hydrogenchloride; tert.-butylnitrite / 1,4-dioxane; ethyl acetate; N,N-dimethyl-formamide / 3 h / -30 °C / Inert atmosphere
2.2: -30 - 20 °C / Inert atmosphere
With
hydrogenchloride; tert.-butylnitrite;
In
1,4-dioxane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1039/c1ob06554h
