Technology Process of C26H27NO2
There total 2 articles about C26H27NO2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: acetic acid / trifluoroacetic acid / 3 h / 90 °C / Inert atmosphere
2: tetrahydrofuran / 5 h / -78 - 0 °C / Inert atmosphere
With
acetic acid;
In
tetrahydrofuran; trifluoroacetic acid;
DOI:10.1039/c2ob25772f
- Guidance literature:
-
In
tetrahydrofuran;
at -78 - 0 ℃;
for 5h;
optical yield given as %ee;
enantioselective reaction;
Inert atmosphere;
DOI:10.1039/c2ob25772f
- Guidance literature:
-
Multi-step reaction with 8 steps
1: dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / tetrahydrofuran / 12 h / Inert atmosphere
2: sodium periodate / tetrahydrofuran; water / 0.33 h / Inert atmosphere
3: sodium tetrahydroborate / methanol / 0.08 h / Inert atmosphere
4: tributylphosphine / tetrahydrofuran / 4 h / Inert atmosphere
5: dihydrogen peroxide / tetrahydrofuran / 6 h / 45 °C / Inert atmosphere
6: triphenylphosphine / tetrahydrofuran; water / 12 h / Inert atmosphere
7: isopropylmagnesium chloride / tetrahydrofuran; benzene / 1 h / 50 °C / Inert atmosphere
8: toluene-4-sulfonic acid / benzene / 24 h / Inert atmosphere
With
dmap; sodium tetrahydroborate; sodium periodate; tributylphosphine; dihydrogen peroxide; isopropylmagnesium chloride; benzotriazol-1-ol; toluene-4-sulfonic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triphenylphosphine;
In
tetrahydrofuran; methanol; water; benzene;
7: Aza-Claisen rearrangement;
DOI:10.1039/c2ob25772f
