2-Ethoxy-5-nitropyrimidine

Base Information

• Chemical Name: 2-Ethoxy-5-nitropyrimidine
• CAS No.: 13207-98-2
• Molecular Formula: C₆H₇N₃O₃
• Molecular Weight: 169.14
• Hs Code.: 2933599090
• NSC Number: 165529
• DSSTox Substance ID: DTXSID50304368
• Wikidata: Q82050240
• Mol file: 13207-98-2.mol

Synonyms:2-ethoxy-5-nitropyrimidine;13207-98-2;Pyrimidine, 2-ethoxy-5-nitro- (8CI,9CI);NSC165529;DTXSID50304368;NSC-165529

Chemical Property of 2-Ethoxy-5-nitropyrimidine

Chemical Property:

• Vapor Pressure: 0.00111mmHg at 25°C
• Boiling Point: 310.3°Cat760mmHg
• Flash Point: 141.4°C
• PSA: 80.83000
• Density: 1.319g/cm³
• LogP: 1.30670
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 169.04874109
• Heavy Atom Count: 12
• Complexity: 151

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=NC=C(C=N1)[N+](=O)[O-]

Technology Process of 2-Ethoxy-5-nitropyrimidine

There total 2 articles about 2-Ethoxy-5-nitropyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-nitro-2-methoxypyrimidine (14001-69-5) + ethanol (64-17-5) → 2-Aethoxy-5-nitro-pyrimidin (13207-98-2)

Guidance literature:

With triethylamine; Heating;

DOI:10.1021/jo00345a036

Reference yield:

→ 2-Aethoxy-5-nitro-pyrimidin (13207-98-2)

Guidance literature:

2-Chlor-5-nitro-pyrimidin, Na-aethylat in A. <Δ>;

upstream raw materials:

5-nitro-2-methoxypyrimidine

ethanol