2-methyl-4-(thiophen-2-yl)but-3-yn-2-ol

Base Information

Chemical Name:2-methyl-4-(thiophen-2-yl)but-3-yn-2-ol
CAS No.:133844-84-5
Molecular Formula:C9H10OS
Molecular Weight:166.244
Hs Code.:2934999090
Mol file:133844-84-5.mol

Synonyms:2-HYDROXY-2-METHYL-4-(2-THIOPHEN-YL)-3-BUTYNE;.2-methyl-4-(2-thienyl)-3-butyn-2-ol;2-methyl-4-(thiophen-2-yl)but-3-yn-2-ol;.2-methyl-4-(thien-2-yl)but-3-yn-2-ol;.2-methyl-4-(2-thienyl)-but-3-yn-2-ol;

Suppliers and Price of 2-methyl-4-(thiophen-2-yl)but-3-yn-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
2-Methyl-4-thiophen-2-yl-but-3-yn-2-ol
1g
$ 661.00

Rieke Metals
2-Methyl-4-thiophen-2-yl-but-3-yn-2-ol
5g
$ 1728.00

American Custom Chemicals Corporation
2-HYDROXY-2-METHYL-4-(2-THIOPHEN-YL)-3-BUTYNE 95.00%
500MG
$ 770.10

Total 2 raw suppliers

Chemical Property of 2-methyl-4-(thiophen-2-yl)but-3-yn-2-ol

Chemical Property:

PSA：48.47000
LogP:1.87050

Purity/Quality:

99% ^*data from raw suppliers

2-Methyl-4-thiophen-2-yl-but-3-yn-2-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-methyl-4-(thiophen-2-yl)but-3-yn-2-ol

There total 8 articles about 2-methyl-4-(thiophen-2-yl)but-3-yn-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1003-09-4
2-bromothiophene

: 115-19-5
2-methyl-but-3-yn-2-ol

: 133844-84-5
2-methyl-4-(thien-2-yl)but-3-yn-2-ol

Guidance literature:: With copper(l) iodide; triethylamine; triphenylphosphine; at 90 ℃; for 48h; Inert atmosphere;
DOI:10.3390/molecules15129157

Reference yield: 91.0%

: 4298-52-6
2-ethynyl-thiophene

: 67-64-1
acetone

: 133844-84-5
2-methyl-4-(thien-2-yl)but-3-yn-2-ol

Guidance literature:: 2-ethynyl-thiophene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

acetone; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.orglett.1c02283

Reference yield: 87.0%

: 3437-95-4,149762-92-5
2-Iodothiophene

: 115-19-5
2-methyl-but-3-yn-2-ol

: 133844-84-5
2-methyl-4-(thien-2-yl)but-3-yn-2-ol

Guidance literature:: With copper(l) iodide; ethanolamine; triphenylphosphine; palladium on activated charcoal; In water; at 80 ℃; for 8h;
DOI:10.1016/j.bmcl.2006.09.041