(S)-2-[(S)-1-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-2-methoxy-cyclohexa-2,5-dienecarbonyloxymethyl]-pyrrolidine-1-carboxylic acid methyl ester

Base Information

• Chemical Name: (S)-2-[(S)-1-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-2-methoxy-cyclohexa-2,5-dienecarbonyloxymethyl]-pyrrolidine-1-carboxylic acid methyl ester
• CAS No.: 94978-42-4
• Molecular Formula: C₂₄H₃₉NO₇
• Molecular Weight: 453.576
• Mol file: 94978-42-4.mol

Synonyms:

Chemical Property of (S)-2-[(S)-1-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-2-methoxy-cyclohexa-2,5-dienecarbonyloxymethyl]-pyrrolidine-1-carboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-[(S)-1-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-2-methoxy-cyclohexa-2,5-dienecarbonyloxymethyl]-pyrrolidine-1-carboxylic acid methyl ester

There total 3 articles about (S)-2-[(S)-1-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-2-methoxy-cyclohexa-2,5-dienecarbonyloxymethyl]-pyrrolidine-1-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-(4,4-Dimethyl-5-oxo-pentyl)-6-oxo-cyclohex-2-enecarboxylic acid (S)-1-pyrrolidin-2-ylmethyl ester (94978-40-2) → (S)-2-[(S)-1-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-2-methoxy-cyclohexa-2,5-dienecarbonyloxymethyl]-pyrrolidine-1-carboxylic acid methyl ester (94978-42-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium bicarbonate

2: hydrogen chloride / methanol / Heating

With hydrogenchloride; sodium hydrogencarbonate; In methanol;

DOI:10.1021/jo00206a049

Reference yield:

(4aS,10aS)-4a-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-2,3,4a,7,10,10a-hexahydro-1H-9-oxa-3a-aza-benzo[f]azulen-4-one (94978-39-9) → (S)-2-[(S)-1-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-2-methoxy-cyclohexa-2,5-dienecarbonyloxymethyl]-pyrrolidine-1-carboxylic acid methyl ester (94978-42-4)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrochloric acid/methanol

2: sodium bicarbonate

3: hydrogen chloride / methanol / Heating

With hydrogenchloride; methanol; sodium hydrogencarbonate; In methanol;

DOI:10.1021/jo00206a049

Reference yield:

(S)-2-[(S)-1-(4,4-Dimethyl-5-oxo-pentyl)-6-oxo-cyclohex-2-enecarbonyloxymethyl]-pyrrolidine-1-carboxylic acid methyl ester (94978-41-3) + trimethyl orthoformate (149-73-5) → (S)-2-[(S)-1-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-2-methoxy-cyclohexa-2,5-dienecarbonyloxymethyl]-pyrrolidine-1-carboxylic acid methyl ester (94978-42-4)

Guidance literature:

With hydrogenchloride; In methanol; Heating;

DOI:10.1021/jo00206a049

upstream raw materials:

(S)-2-[(S)-1-(4,4-Dimethyl-5-oxo-pentyl)-6-oxo-cyclohex-2-enecarbonyloxymethyl]-pyrrolidine-1-carboxylic acid methyl ester

trimethyl orthoformate

(S)-1-(4,4-Dimethyl-5-oxo-pentyl)-6-oxo-cyclohex-2-enecarboxylic acid (S)-1-pyrrolidin-2-ylmethyl ester

(4aS,10aS)-4a-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-2,3,4a,7,10,10a-hexahydro-1H-9-oxa-3a-aza-benzo[f]azulen-4-one

Downstream raw materials:

(S)-1-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-2-methoxy-cyclohexa-2,5-dienecarboxylic acid methyl ester

(S)-1-(4,4-Dimethyl-5-oxo-pentyl)-6-oxo-cyclohexa-2,4-dienecarboxylic acid methyl ester

(S)-1-(4-Cyano-4,4-dimethyl-butyl)-6-oxo-cyclohexa-2,4-dienecarboxylic acid methyl ester

(S)-1-(5,5-Dimethoxy-4,4-dimethyl-pentyl)-6-oxo-cyclohexa-2,4-dienecarboxylic acid methyl ester