C₅₀H₅₆N₄O₁₀S₂

Base Information

• Chemical Name: C₅₀H₅₆N₄O₁₀S₂
• CAS No.: 1334138-60-1
• Molecular Formula: C₅₀H₅₆N₄O₁₀S₂
• Molecular Weight: 937.147
• Mol file: 1334138-60-1.mol

Synonyms:

Chemical Property of C₅₀H₅₆N₄O₁₀S₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₀H₅₆N₄O₁₀S₂

There total 11 articles about C₅₀H₅₆N₄O₁₀S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-(4-methoxyphenyl)-2-naphthoic acid (132292-17-2) → C50H56N4O10S2 (1334138-60-1)

Guidance literature:

Multi-step reaction with 4 steps

1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 0 - 20 °C / Inert atmosphere

2: triethylamine / dichloromethane / 0 - 20 °C

3: potassium carbonate / acetone / Reflux

4: potassium carbonate / acetone / Reflux

With thionyl chloride; potassium carbonate; triethylamine; N,N-dimethyl-formamide; In dichloromethane; acetone;

DOI:10.1002/cmdc.201100207

Reference yield:

ethyl 6-(4-methoxyphenyl)-2-naphthoate (1334137-82-4) → C50H56N4O10S2 (1334138-60-1)

Guidance literature:

Multi-step reaction with 5 steps

1.1: water; sodium hydroxide / ethanol / 20 - 80 °C

1.2: pH 7

2.1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 0 - 20 °C / Inert atmosphere

3.1: triethylamine / dichloromethane / 0 - 20 °C

4.1: potassium carbonate / acetone / Reflux

5.1: potassium carbonate / acetone / Reflux

With thionyl chloride; water; potassium carbonate; triethylamine; N,N-dimethyl-formamide; sodium hydroxide; In ethanol; dichloromethane; acetone;

DOI:10.1002/cmdc.201100207

Reference yield:

tert-butyl 4-(3-hydroxy-4-methoxybenzoyl)-1-piperazinecarboxylate (1334137-74-4) → C50H56N4O10S2 (1334138-60-1)

Guidance literature:

Multi-step reaction with 4 steps

1: trifluoroacetic acid / dichloromethane / 2 h / 0 - 20 °C

2: triethylamine / dichloromethane / 0 - 20 °C

3: potassium carbonate / acetone / Reflux

4: potassium carbonate / acetone / Reflux

With potassium carbonate; triethylamine; trifluoroacetic acid; In dichloromethane; acetone;

DOI:10.1002/cmdc.201100207

upstream raw materials:

6-(4-methoxyphenyl)-2-naphthoic acid

ethyl 6-(4-methoxyphenyl)-2-naphthoate

tert-butyl 4-(3-hydroxy-4-methoxybenzoyl)-1-piperazinecarboxylate

(3-hydroxy-4-methoxybenzoyl)-1-piperazine

Downstream raw materials:

(11aS)-7-methoxy-8-(3-(2-methoxy-5-(4-(6-(4-methoxyphenyl)-2-naphthoyl)piperazine-1-carbonyl)phenoxy)propoxy)-2,3-dihydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5(11aH)-one

Refernces