4-Bromo-3'-methoxybenzhydryl chloride

Base Information

• Chemical Name: 4-Bromo-3'-methoxybenzhydryl chloride
• CAS No.: 134446-27-8
• Molecular Formula: C14H12BrClO
• Molecular Weight: 311.606
• DSSTox Substance ID: DTXSID101235520
• Mol file: 134446-27-8.mol

Synonyms:4-bromo-3'-methoxybenzhydryl chloride;SCHEMBL6659757;JRWKTTRQZFECCY-UHFFFAOYSA-N;DTXSID101235520;AKOS006214100;134446-27-8;1-[(4-Bromophenyl)chloromethyl]-3-methoxybenzene

Chemical Property of 4-Bromo-3'-methoxybenzhydryl chloride

Chemical Property:

• XLogP3: 4.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 309.97601
• Heavy Atom Count: 17
• Complexity: 228

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)C(C2=CC=C(C=C2)Br)Cl

Technology Process of 4-Bromo-3'-methoxybenzhydryl chloride

There total 2 articles about 4-Bromo-3'-methoxybenzhydryl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-bromo-phenyl)-(3-methoxy-phenyl)-methanol (134446-26-7) + 1.4-dibromobenzene (106-37-6) + sodium hydrogensulfite + 3-methoxy-benzaldehyde (591-31-1) → (+/-)-4-Bromo-α-(3-methoxybenzene)benzyl Chloride (134446-27-8)

Guidance literature:

With sodium hydroxide; n-butyllithium; thionyl chloride; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; water; toluene;

Reference yield:

→ (+-)-4-Bromo-α-(3-methoxybenzene)benzyl Alcohol + (+/-)-4-Bromo-α-(3-methoxybenzene)benzyl Chloride (134446-27-8)

Guidance literature:

upstream raw materials:

(4-bromo-phenyl)-(3-methoxy-phenyl)-methanol

1.4-dibromobenzene

3-methoxy-benzaldehyde