Benzenemethanol, a-(4-bromophenyl)-3-methoxy-

Base Information

• Chemical Name: Benzenemethanol, a-(4-bromophenyl)-3-methoxy-
• CAS No.: 134446-26-7
• Molecular Formula: C14H13BrO2
• Molecular Weight: 293.16
• Mol file: 134446-26-7.mol

Synonyms:(4-bromophenyl)-(3-methoxyphenyl)-methanol;(4-bromophenyl)(3-methoxyphenyl)methanol;(4-bromophenyl)(3-methoxyphenyl)-methanol;

Chemical Property of Benzenemethanol, a-(4-bromophenyl)-3-methoxy-

Chemical Property:

• PSA: 29.46000
• LogP: 3.53940

Purity/Quality:

97% ^*data from raw suppliers

(4-BROMOPHENYL)(3-METHOXYPHENYL)METHANOL ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenemethanol, a-(4-bromophenyl)-3-methoxy-

There total 3 articles about Benzenemethanol, a-(4-bromophenyl)-3-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(3-methoxyphenyl)magnesium bromide (36282-40-3) + 4-bromo-benzaldehyde (1122-91-4) → (4-bromo-phenyl)-(3-methoxy-phenyl)-methanol (134446-26-7)

Guidance literature:

(3-methoxyphenyl)magnesium bromide; 4-bromo-benzaldehyde; In tetrahydrofuran; at 80 ℃; for 3h; Inert atmosphere;

With water; sodium chloride; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.ejmech.2011.09.004

Reference yield: 82.0%

1-chloro-3-methoxy-benzene (2845-89-8) + 4-bromo-benzaldehyde (1122-91-4) → (4-bromo-phenyl)-(3-methoxy-phenyl)-methanol (134446-26-7)

Guidance literature:

1-chloro-3-methoxy-benzene; With lithium 4,4′-di-tert-butylbiphenylide; In tetrahydrofuran; diethyl ether; decane; at -95 ℃; for 0.0833333h; Inert atmosphere; Schlenk technique;

4-bromo-benzaldehyde; In tetrahydrofuran; diethyl ether; decane; at -95 - 20 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1055/s-0034-1380697

Reference yield:

ammonium chloride (NH4Cl) + 2-bromoanisole (578-57-4) + 4-bromo-benzaldehyde (1122-91-4) → (4-bromo-phenyl)-(3-methoxy-phenyl)-methanol (134446-26-7)

Guidance literature:

With magnesium; In tetrahydrofuran;

upstream raw materials:

2-bromoanisole

4-bromo-benzaldehyde

(3-methoxyphenyl)magnesium bromide

1-chloro-3-methoxy-benzene

Downstream raw materials:

(4-bromophenyl)-(3-methoxyphenyl)-methanone

(+/-)-4-Bromo-α-(3-methoxybenzene)benzyl Chloride

(3'-chloro-4'-hydroxybiphenyl-4-yl)-(3-hydroxyphenyl)-methanone

(3'-chloro-4'-hydroxybiphenyl-4-yl)-(3-methoxyphenyl)-methanone