C₃₄H₄₂O₈Se

Base Information

• Chemical Name: C₃₄H₄₂O₈Se
• CAS No.: 110906-67-7
• Molecular Formula: C₃₄H₄₂O₈Se
• Molecular Weight: 657.663
• Mol file: 110906-67-7.mol

Synonyms:

Chemical Property of C₃₄H₄₂O₈Se

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₄H₄₂O₈Se

There total 13 articles about C₃₄H₄₂O₈Se which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(2R,3R,4R,6S)-4-((2R,3S,4S,5R,6R)-4,5-Bis-benzyloxy-6-methyl-3-phenylselanyl-tetrahydro-pyran-2-yloxy)-6-methoxy-2,4-dimethyl-tetrahydro-pyran-3-ol (110906-65-5) → C34H42O8Se (110906-67-7,111136-33-5)

Guidance literature:

With sodium periodate; In methanol; water; at 20 ℃; for 1h;

DOI:10.1016/S0040-4039(00)95922-7

Reference yield:

methyl 4,6-O-(R)-benzylidene-2-deoxy-α-D-erythrohexopyranosid-3-ulose (63598-31-2) → C34H42O8Se (110906-67-7,111136-33-5)

Guidance literature:

Multi-step reaction with 6 steps

1: 75 percent / NaNH₂ / tetrahydrofuran / 0.25 h / 20 °C

2: 1.) Hg(OAc)2 2.) NaBH₄ / 1.) THF-water, 20 deg C, 30 min 2.) aq. NaOH, 20 deg C, 5 min

3: 95 percent / N-bromosuccinimide, BaCO₃ / CCl₄ / 6 h / Heating

4: 84 percent / LiAlH₄ / tetrahydrofuran / 6 h / Heating

5: 2.) sym-collidine / 2.) CH₃CN, 0 deg C, 1 h

6: 98 percent / NaIO₄ / methanol; H₂O / 1 h / 20 °C

With 2,4,6-trimethyl-pyridine; sodium tetrahydroborate; sodium periodate; N-Bromosuccinimide; lithium aluminium tetrahydride; mercury(II) diacetate; sodium amide; barium carbonate; In tetrahydrofuran; methanol; tetrachloromethane; water;

DOI:10.1016/S0040-4039(00)95922-7

Reference yield:

methyl 4,6-O-benzylidene-2-deoxy-3-C-methyl-α-D-arabino-hexopyranoside (100100-70-7) → C34H42O8Se (110906-67-7,111136-33-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 95 percent / N-bromosuccinimide, BaCO₃ / CCl₄ / 6 h / Heating

2: 84 percent / LiAlH₄ / tetrahydrofuran / 6 h / Heating

3: 2.) sym-collidine / 2.) CH₃CN, 0 deg C, 1 h

4: 98 percent / NaIO₄ / methanol; H₂O / 1 h / 20 °C

With 2,4,6-trimethyl-pyridine; sodium periodate; N-Bromosuccinimide; lithium aluminium tetrahydride; barium carbonate; In tetrahydrofuran; methanol; tetrachloromethane; water;

DOI:10.1016/S0040-4039(00)95922-7

upstream raw materials:

(2R,3R,4R,6S)-4-((2R,3S,4S,5R,6R)-4,5-Bis-benzyloxy-6-methyl-3-phenylselanyl-tetrahydro-pyran-2-yloxy)-6-methoxy-2,4-dimethyl-tetrahydro-pyran-3-ol

Phenylselenyl chloride

methyl 2,6-dideoxy-3-C-methyl-α-D-arabino-hexopyranoside

methyl 4,6-O-(R)-benzylidene-2-deoxy-α-D-erythrohexopyranosid-3-ulose

Downstream raw materials:

C₂₈H₃₆O₇

C₂₈H₃₆O₇

(3R,4R,5R)-3,4-Bis-benzyloxy-5-hydroxy-hexanoic acid (2R,3R,4R,6S)-3-hydroxy-6-methoxy-2,4-dimethyl-tetrahydro-pyran-4-yl ester

(3R,4R,5R)-3,4-Bis-benzyloxy-5-hydroxy-hexanoic acid (2R,3R,4R,6S)-4-hydroxy-6-methoxy-2,4-dimethyl-tetrahydro-pyran-3-yl ester