Tetrakis(1-Methylethyl)-2,10-diMethyl-3,3,9,9-4,8-dioxa-3,9-disilaundecan-6-ol

Base Information

• Chemical Name: Tetrakis(1-Methylethyl)-2,10-diMethyl-3,3,9,9-4,8-dioxa-3,9-disilaundecan-6-ol
• CAS No.: 98264-26-7
• Molecular Formula: C₂₁H₄₈O₃Si₂
• Molecular Weight: 404.781
• Mol file: 98264-26-7.mol

Synonyms:

Chemical Property of Tetrakis(1-Methylethyl)-2,10-diMethyl-3,3,9,9-4,8-dioxa-3,9-disilaundecan-6-ol

Chemical Property:

• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: Chloroform, DCM, Methanol

Purity/Quality:

1,3-O-Bis(triisopropylsilyl)Glycerol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Tetrakis(1-methylethyl)-2,10-dimethyl-3,3,9,9-4,8-dioxa-3,9-disilaundecan-6-ol is an protected glycerol (G598400), used both in sample preparation and gel formation for polyacrylamide gel electrophoresis.

Technology Process of Tetrakis(1-Methylethyl)-2,10-diMethyl-3,3,9,9-4,8-dioxa-3,9-disilaundecan-6-ol

There total 2 articles about Tetrakis(1-Methylethyl)-2,10-diMethyl-3,3,9,9-4,8-dioxa-3,9-disilaundecan-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

triisopropylsilyl chloride (13154-24-0) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 1,3-Bis-triisopropylsilanyloxy-propan-2-ol (98264-26-7)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1016/S0040-4039(99)00028-3

Reference yield: 85.0%

chlorotriisopropylsilane (6485-79-6) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 1,3-Bis-triisopropylsilanyloxy-propan-2-ol (98264-26-7)

Guidance literature:

With 1H-imidazole; cesium fluoride; In tetrahydrofuran; N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1016/0022-328X(85)87167-9

Reference yield: 94.0%

all cis 5,8,11,14-eicosatetraenoic acid (506-32-1,236743-58-1) + 1,3-Bis-triisopropylsilanyloxy-propan-2-ol (98264-26-7) → (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid 2-triisopropylsilanyloxy-1-triisopropylsilanyloxymethyl-ethyl ester (223259-26-5)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 24h; Ambient temperature;

DOI:10.1016/S0040-4039(99)00028-3

upstream raw materials:

chlorotriisopropylsilane

glycerol

triisopropylsilyl chloride

Downstream raw materials:

(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid 2-triisopropylsilanyloxy-1-triisopropylsilanyloxymethyl-ethyl ester

Refernces

• 1、 Horner, Leopold,Mathias, Johann. "CHEMOSELEKTIVE MONO- UND DISILYLETHERBILDUNG AUS TERTIAEREN UND SEKUNDAEREN SILANEN". . p. 155 - 174. Retrieved 2007/10/02.