(2S,4S)-4-((2R,3R,4R,5S,6R)-3-Acetylamino-4-benzyloxy-6-benzyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-(2,5-dioxo-pyrrolidin-1-yl) ester

Base Information

Chemical Name:(2S,4S)-4-((2R,3R,4R,5S,6R)-3-Acetylamino-4-benzyloxy-6-benzyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-(2,5-dioxo-pyrrolidin-1-yl) ester
CAS No.:115516-56-8
Molecular Formula:C₃₉H₄₃N₃O₁₂
Molecular Weight:745.783
Hs Code.:

(2S,4S)-4-((2R,3R,4R,5S,6R)-3-Acetylamino-4-benzyloxy-6-benzyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-(2,5-dioxo-pyrrolidin-1-yl) ester

Synonyms:

Suppliers and Price of (2S,4S)-4-((2R,3R,4R,5S,6R)-3-Acetylamino-4-benzyloxy-6-benzyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-(2,5-dioxo-pyrrolidin-1-yl) ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,4S)-4-((2R,3R,4R,5S,6R)-3-Acetylamino-4-benzyloxy-6-benzyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-(2,5-dioxo-pyrrolidin-1-yl) ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,4S)-4-((2R,3R,4R,5S,6R)-3-Acetylamino-4-benzyloxy-6-benzyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-(2,5-dioxo-pyrrolidin-1-yl) ester

There total 9 articles about (2S,4S)-4-((2R,3R,4R,5S,6R)-3-Acetylamino-4-benzyloxy-6-benzyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-(2,5-dioxo-pyrrolidin-1-yl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 54400-75-8,64650-83-5,88903-97-3,116347-86-5,140849-88-3,144300-01-6,54400-77-0
allyl 2-acetamido-2-deoxy-β-D-glucopyranoside

: 115516-56-8
(2S,4S)-4-((2R,3R,4R,5S,6R)-3-Acetylamino-4-benzyloxy-6-benzyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-(2,5-dioxo-pyrrolidin-1-yl) ester

Guidance literature:: Multi-step reaction with 7 steps

1: 66 percent / TsOH / dimethylformamide

2: 91 percent / NaOH / dimethylformamide

3: 87 percent / NaBH₃CN, HCl / tetrahydrofuran

4: 1.) t-BuOK / 1.) DMSO 2.) pyridine

5: 84 percent / I₂, DABCO / tetrahydrofuran

6: 54 percent / TsOH / 1,2-dichloro-ethane

7: 1.) NaOH 2.) DCC / 1.) MeOH

With 1,4-diaza-bicyclo[2.2.2]octane; hydrogenchloride; sodium hydroxide; potassium tert-butylate; iodine; sodium cyanoborohydride; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)81081-9

Reference yield:

: 63064-48-2,116288-58-5,117299-90-8,126778-02-7,28738-44-5
allyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside

: 115516-56-8
(2S,4S)-4-((2R,3R,4R,5S,6R)-3-Acetylamino-4-benzyloxy-6-benzyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-(2,5-dioxo-pyrrolidin-1-yl) ester

Guidance literature:: Multi-step reaction with 8 steps

1: 98 percent / MeONa

2: 66 percent / TsOH / dimethylformamide

3: 91 percent / NaOH / dimethylformamide

4: 87 percent / NaBH₃CN, HCl / tetrahydrofuran

5: 1.) t-BuOK / 1.) DMSO 2.) pyridine

6: 84 percent / I₂, DABCO / tetrahydrofuran

7: 54 percent / TsOH / 1,2-dichloro-ethane

8: 1.) NaOH 2.) DCC / 1.) MeOH

With 1,4-diaza-bicyclo[2.2.2]octane; hydrogenchloride; sodium hydroxide; potassium tert-butylate; iodine; sodium methylate; sodium cyanoborohydride; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)81081-9

Reference yield:

: 3006-60-8,4539-83-7,6730-10-5,7772-79-4,7784-54-5,10385-50-9,26151-16-6,76375-60-5,76375-61-6,95341-98-3,95341-99-4,134451-91-5,134451-96-0,136982-81-5,145375-11-7,148347-15-3,14086-90-9
2-acetamido-3,4,6-tri-O-acetyl-D-glucopyranosyl acetate

: 115516-56-8
(2S,4S)-4-((2R,3R,4R,5S,6R)-3-Acetylamino-4-benzyloxy-6-benzyloxymethyl-5-hydroxy-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-(2,5-dioxo-pyrrolidin-1-yl) ester

Guidance literature:: Multi-step reaction with 9 steps

2: 98 percent / MeONa

3: 66 percent / TsOH / dimethylformamide

4: 91 percent / NaOH / dimethylformamide

5: 87 percent / NaBH₃CN, HCl / tetrahydrofuran

6: 1.) t-BuOK / 1.) DMSO 2.) pyridine

7: 84 percent / I₂, DABCO / tetrahydrofuran

8: 54 percent / TsOH / 1,2-dichloro-ethane

9: 1.) NaOH 2.) DCC / 1.) MeOH

With 1,4-diaza-bicyclo[2.2.2]octane; hydrogenchloride; sodium hydroxide; potassium tert-butylate; iodine; sodium methylate; sodium cyanoborohydride; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)81081-9