4-[[[4-[[[4-[[p-(methoxycarbonyl)phenylenecarbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-N-[3-(N,N-dimethylamino)propyl]-2-pyrrolecarboxamide

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Chemical Name:4-[[[4-[[[4-[[p-(methoxycarbonyl)phenylenecarbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-N-[3-(N,N-dimethylamino)propyl]-2-pyrrolecarboxamide
CAS No.:282088-96-4
Molecular Formula:C₃₄H₄₂N₈O₆
Molecular Weight:658.757
Hs Code.:

4-[[[4-[[[4-[[p-(methoxycarbonyl)phenylenecarbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-N-[3-(N,N-dimethylamino)propyl]-2-pyrrolecarboxamide

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Chemical Property of 4-[[[4-[[[4-[[p-(methoxycarbonyl)phenylenecarbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-N-[3-(N,N-dimethylamino)propyl]-2-pyrrolecarboxamide

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Technology Process of 4-[[[4-[[[4-[[p-(methoxycarbonyl)phenylenecarbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-N-[3-(N,N-dimethylamino)propyl]-2-pyrrolecarboxamide

There total 2 articles about 4-[[[4-[[[4-[[p-(methoxycarbonyl)phenylenecarbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-N-[3-(N,N-dimethylamino)propyl]-2-pyrrolecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 65361-32-2
nitrolexitropsin

: 282088-96-4
4-[[[4-[[[4-[[p-(methoxycarbonyl)phenylenecarbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-N-[3-(N,N-dimethylamino)propyl]-2-pyrrolecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: PtO₂ / methanol / 20 °C / 760 Torr

2.1: HOBt; DCC / dimethylformamide / 4 h / 20 °C

2.2: dimethylformamide / 0 - 20 °C

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; platinum(IV) oxide; In methanol; N,N-dimethyl-formamide; 1.1: Reduction / 2.1: Esterification;
DOI:10.1248/cpb.48.603

Reference yield:

: 17833-56-6
ester monomethylique de l'acide p-phenylene diacetique

: 78486-18-7
3-(1-methyl-4-(1-methyl-4-(1-methyl-4-aminopyrrole-2-carboxamido)pyrrole-2-carboxamido)pyrrole-2-carboxamido)dimethylaminopropane

: 282088-96-4
4-[[[4-[[[4-[[p-(methoxycarbonyl)phenylenecarbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-2-pyrrolyl]carbonyl]amino]-1-methyl-N-[3-(N,N-dimethylamino)propyl]-2-pyrrolecarboxamide

Guidance literature:: ester monomethylique de l'acide p-phenylene diacetique; With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

3-(1-methyl-4-(1-methyl-4-(1-methyl-4-aminopyrrole-2-carboxamido)pyrrole-2-carboxamido)pyrrole-2-carboxamido)dimethylaminopropane; In N,N-dimethyl-formamide; at 0 - 20 ℃;
DOI:10.1248/cpb.48.603