7-O-Prenylscopoletin

Base Information

• Chemical Name: 7-O-Prenylscopoletin
• CAS No.: 13544-37-1
• Molecular Formula: C15H16O4
• Molecular Weight: 260.28500
• Mol file: 13544-37-1.mol

Synonyms:6-methoxy-7-(3',3'-dimethylallyloxy)-coumarin;.7-(3-methyl-2-butenyloxy)-6-methoxycoumarin;.6-methoxy-7-(3-methyl-2-butenyloxy)coumarin;.7-(3,3-dimethylallyloxy)-6-methoxycoumarin;.scopoletin-(3'-methyl-but-2'-en-1'-yl)ether;.6-methoxy-7-(3'3'-dimethylallyloxy)-coumarin;

Chemical Property of 7-O-Prenylscopoletin

Chemical Property:

• Melting Point: 80-81 °C
• Boiling Point: 422.9±45.0 °C(Predicted)
• PSA: 48.67000
• Density: 1.159
• LogP: 3.14660

Purity/Quality:

Analysis control,HPLC≥95% ^*data from raw suppliers

Prenyletin methyl ether ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-O-Prenylscopoletin

There total 3 articles about 7-O-Prenylscopoletin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

7-hydroxy-6-methoxy-2H-1-benzopyran-2-one (92-61-5) + prenyl bromide (870-63-3) → 7-(3-methyl-2-butenyloxy)-6-methoxycoumarin (13544-37-1)

Guidance literature:

With potassium carbonate; In acetone; at 50 ℃; for 15h;

DOI:10.1055/s-2004-829139

Reference yield:

2-hydroxy-4,5-dimethoxybenzaldehyde (14382-91-3) + methyl (triphenylphosphoranylidene)acetate (21204-67-1,2605-67-6) + prenyl bromide (870-63-3) → 7-(3-methyl-2-butenyloxy)-6-methoxycoumarin (13544-37-1)

Guidance literature:

2-hydroxy-4,5-dimethoxybenzaldehyde; methyl (triphenylphosphoranylidene)acetate; With N,N-diethylaniline; for 4h; Heating;

prenyl bromide; With potassium carbonate; In acetone; for 15h; Heating;

DOI:10.1016/j.bmc.2009.08.002

Reference yield:

→ 7-(3-methyl-2-butenyloxy)-6-methoxycoumarin (13544-37-1)

Guidance literature:

Scopoletin 6, 3,3-Dimethylallylbromid;

DOI:10.1016/S0040-4020(01)92484-6

upstream raw materials:

7-hydroxy-6-methoxy-2H-1-benzopyran-2-one

prenyl bromide

2-hydroxy-4,5-dimethoxybenzaldehyde

methyl (triphenylphosphoranylidene)acetate

Downstream raw materials:

8-(1,1-Dimethylallyl)-scopoletin