Technology Process of C19H23NO3
There total 4 articles about C19H23NO3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
toluene;
for 48h;
Reflux;
Inert atmosphere;
DOI:10.1002/chem.201103576
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / dichloromethane / 72 h / 20 °C
2: palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 48 h / Reflux; Inert atmosphere
With
palladium 10% on activated carbon; hydrogen; palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
dichloromethane; toluene;
2: Buchwald-Hartwig coupling;
DOI:10.1002/chem.201103576
- Guidance literature:
-
Multi-step reaction with 3 steps
1: dmap; triethylamine / dichloromethane / 24 h / 20 °C
2: palladium 10% on activated carbon; hydrogen / dichloromethane / 72 h / 20 °C
3: palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 48 h / Reflux; Inert atmosphere
With
dmap; palladium 10% on activated carbon; hydrogen; palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triethylamine;
In
dichloromethane; toluene;
3: Buchwald-Hartwig coupling;
DOI:10.1002/chem.201103576
