2-[3-(Oxiran-2-ylmethoxy)phenyl]-1,3,4-oxadiazole

Base Information

Chemical Name:2-[3-(Oxiran-2-ylmethoxy)phenyl]-1,3,4-oxadiazole
CAS No.:79463-12-0
Molecular Formula:C₁₁H₁₀N₂O₃
Molecular Weight:218.212
Hs Code.:
DSSTox Substance ID:DTXSID501238914

Synonyms:79463-12-0;SCHEMBL11168248;DTXSID501238914;2-[3-(2-Oxiranylmethoxy)phenyl]-1,3,4-oxadiazole

Suppliers and Price of 2-[3-(Oxiran-2-ylmethoxy)phenyl]-1,3,4-oxadiazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[3-(Oxiran-2-ylmethoxy)phenyl]-1,3,4-oxadiazole

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:218.06914219
Heavy Atom Count:16
Complexity:239

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(O1)COC2=CC=CC(=C2)C3=NN=CO3

Technology Process of 2-[3-(Oxiran-2-ylmethoxy)phenyl]-1,3,4-oxadiazole

There total 3 articles about 2-[3-(Oxiran-2-ylmethoxy)phenyl]-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 5378-29-0
2-(3-hydroxyphenyl)-1,3,4-oxadiazole

: 3132-64-7,82584-73-4
1,2-Epoxy-3-bromopropane

: 79463-12-0
2,3-epoxypropoxy-3-(1,3,4-oxadiazol-2-yl)benzene

Guidance literature:: With sodium hydride; In dimethyl sulfoxide; for 7h; Ambient temperature;
DOI:10.1016/S0040-4020(01)85962-7

Reference yield:

: 19438-10-9
methyl 3-hydroxybenzoate

: 79463-12-0
2,3-epoxypropoxy-3-(1,3,4-oxadiazol-2-yl)benzene

Guidance literature:: Multi-step reaction with 3 steps

1: N₂H_4.H₂O / methanol

2: 86 percent / 22 h / Heating

3: 53 percent / NaH / dimethylsulfoxide / 7 h / Ambient temperature

With sodium hydride; hydrazine hydrate; In methanol; dimethyl sulfoxide;
DOI:10.1016/S0040-4020(01)85962-7

Reference yield:

: 5818-06-4
3-hydroxybenzoic hydrazide

: 79463-12-0
2,3-epoxypropoxy-3-(1,3,4-oxadiazol-2-yl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / 22 h / Heating

2: 53 percent / NaH / dimethylsulfoxide / 7 h / Ambient temperature

With sodium hydride; In dimethyl sulfoxide;
DOI:10.1016/S0040-4020(01)85962-7