077943-81-8

Base Information

• Chemical Name: 077943-81-8
• CAS No.: 77943-81-8
• Molecular Formula: C₁₉H₂₈O₆SSi
• Molecular Weight: 412.579
• Mol file: 77943-81-8.mol

Synonyms:

Chemical Property of 077943-81-8

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 077943-81-8

There total 10 articles about 077943-81-8 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acrolein dimer (100-73-2) → {(Z)-1-Benzenesulfonyl-2-[(1S,2R,4R,6S)-2-(2-methoxy-ethoxy)-3,7-dioxa-bicyclo[4.1.0]hept-4-yl]-vinyl}-trimethyl-silane (77890-93-8,77943-81-8)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrahydrofuran; hexane / Ambient temperature

2: 92 percent / pyridine / CH₂Cl₂ / 0.5 h / 0 °C

4: MCPBA / CH₂Cl₂ / 72 h / Ambient temperature

With pyridine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1021/jo00193a015

Reference yield:

acrolein dimer (100-73-2) → {(Z)-1-Benzenesulfonyl-2-[(1R,2R,4R,6R)-2-(2-methoxy-ethoxy)-3,7-dioxa-bicyclo[4.1.0]hept-4-yl]-vinyl}-trimethyl-silane (77943-81-8)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrahydrofuran; hexane / Ambient temperature

2: 92 percent / pyridine / CH₂Cl₂ / 0.5 h / 0 °C

4: MCPBA / CH₂Cl₂ / 72 h / Ambient temperature

With pyridine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1021/jo00193a015

Reference yield:

lithium bis(trimethylsilyl)(phenylthio)methylide (62762-44-1) → {(Z)-1-Benzenesulfonyl-2-[(1S,2R,4R,6S)-2-(2-methoxy-ethoxy)-3,7-dioxa-bicyclo[4.1.0]hept-4-yl]-vinyl}-trimethyl-silane (77890-93-8,77943-81-8)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrahydrofuran; hexane / Ambient temperature

2: 92 percent / pyridine / CH₂Cl₂ / 0.5 h / 0 °C

4: MCPBA / CH₂Cl₂ / 72 h / Ambient temperature

With pyridine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1021/jo00193a015

upstream raw materials:

{(Z)-1-Benzenesulfonyl-2-[(2S,6S)-6-(2-methoxy-ethoxy)-3,6-dihydro-2H-pyran-2-yl]-vinyl}-trimethyl-silane

acrolein dimer

lithium bis(trimethylsilyl)(phenylthio)methylide

[(E)-2-(3,4-Dihydro-2H-pyran-2-yl)-1-phenylsulfanyl-vinyl]-trimethyl-silane

Downstream raw materials:

(1S,2S,4S,6S)-4-((R)-2-Benzenesulfonyl-1-methyl-ethyl)-2-(2-methoxy-ethoxy)-3,7-dioxa-bicyclo[4.1.0]heptane

(E)-(2R,5S,6R)-7-Benzenesulfonyl-2,3,3-trimethoxy-6,8-dimethyl-undec-9-ene-1,5-diol

(1S,2S,4S,6S)-4-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-methoxy-ethoxy)-3,7-dioxa-bicyclo[4.1.0]heptane

(3S,4R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-chloro-ethoxy)-3-methoxy-tetrahydro-pyran-4-ol