Bua3Z6M6DS

Base Information

Chemical Name:Bua3Z6M6DS
CAS No.:151909-79-4
Molecular Formula:C₁₃H₁₅ClN₂O
Molecular Weight:250.728
Hs Code.:
UNII:BUA3Z6M6DS

Synonyms:BUA3Z6M6DS;4-(4-chlorophenyl)-1-(1H-imidazol-1-yl)-2-butanol, (S)-;1H-Imidazole-1-ethanol, alpha-[2-(4-chlorophenyl)ethyl]-, (S)-;151909-79-4

Suppliers and Price of Bua3Z6M6DS

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Bua3Z6M6DS

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:250.0872908
Heavy Atom Count:17
Complexity:220

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1CCC(CN2C=CN=C2)O)Cl
Isomeric SMILES:C1=CC(=CC=C1CC[C@@H](CN2C=CN=C2)O)Cl

Technology Process of Bua3Z6M6DS

There total 2 articles about Bua3Z6M6DS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 874-72-6
4-chlorobenzylmagnesium chloride

: 151909-79-4
(2S)-1-<2-hydroxy-4-(4-chlorophenyl)butyl>-1H-imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Li₂CuCl₄ / 1.) Et₂O, -35 deg C, 45 min, 2.) Et₂O, THF, -35 deg C, 2 h

2: 1.) NaH / 1.) DMF, RT, 30 min, 2.) DMF, 75 deg C, 24 h

With dilithium tetrachlorocuprate; sodium hydride;
DOI:10.1016/S0957-4166(00)80353-5

Reference yield:

: 288-32-4
1H-imidazole

: 151837-96-6
(2S)-1-(p-toluenesulphonyloxy)-4-(4-chlorophenyl)butan-2-ol

: 151909-79-4
(2S)-1-<2-hydroxy-4-(4-chlorophenyl)butyl>-1H-imidazole

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMF, RT, 30 min, 2.) DMF, 75 deg C, 24 h;
DOI:10.1016/S0957-4166(00)80353-5

Reference yield:

: 151909-79-4
(2S)-1-<2-hydroxy-4-(4-chlorophenyl)butyl>-1H-imidazole

: 67085-13-6
(2R)-1-<2-(2,6-dichlorophenylthio)-4-(4-chlorophenyl)butyl>-1H-imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / tetrahydrofuran / 1 h / Ambient temperature

2: K₂CO₃ / acetone / 16 h / Heating

With potassium carbonate; triethylamine; In tetrahydrofuran; acetone;
DOI:10.1016/S0957-4166(00)80353-5