C₂₅H₂₈F₃N₇O

Base Information

• Chemical Name: C₂₅H₂₈F₃N₇O
• CAS No.: 1295479-53-6
• Molecular Formula: C₂₅H₂₈F₃N₇O
• Molecular Weight: 499.539
• Mol file: 1295479-53-6.mol

Synonyms:

Chemical Property of C₂₅H₂₈F₃N₇O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₂₈F₃N₇O

There total 7 articles about C₂₅H₂₈F₃N₇O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2', 4'-difluorophenyl)-1-butylamino-3-(1''', 2''', 4''') triazol-1'''-yl-propan-2-ol (149764-68-1) → C25H28F3N7O (1295479-53-6)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile / 6 h / 20 °C

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / dimethyl sulfoxide

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In dimethyl sulfoxide; acetonitrile;

DOI:10.1016/j.cclet.2010.11.029

Reference yield:

1,3-Difluorobenzene (372-18-9) → C25H28F3N7O (1295479-53-6)

Guidance literature:

Multi-step reaction with 6 steps

1.1: aluminum (III) chloride / 5 h / 50 °C

2.1: sodium hydrogencarbonate / toluene / 5 h / Reflux

3.1: cetyltrimethylammonim bromide; sodium hydroxide / 3 h / 60 °C

3.2: 1 h / 0 °C

4.1: triethylamine / ethanol / 6 h / Reflux

5.1: acetonitrile / 6 h / 20 °C

6.1: copper(ll) sulfate pentahydrate; sodium L-ascorbate / dimethyl sulfoxide

With aluminum (III) chloride; copper(ll) sulfate pentahydrate; cetyltrimethylammonim bromide; sodium hydrogencarbonate; sodium L-ascorbate; triethylamine; sodium hydroxide; In ethanol; dimethyl sulfoxide; toluene; acetonitrile;

DOI:10.1016/j.cclet.2010.11.029

Reference yield:

2-chloro-1-(2,4-dichlorophenyl)ethanone (51336-94-8) → C25H28F3N7O (1295479-53-6)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hydrogencarbonate / toluene / 5 h / Reflux

2.1: cetyltrimethylammonim bromide; sodium hydroxide / 3 h / 60 °C

2.2: 1 h / 0 °C

3.1: triethylamine / ethanol / 6 h / Reflux

4.1: acetonitrile / 6 h / 20 °C

5.1: copper(ll) sulfate pentahydrate; sodium L-ascorbate / dimethyl sulfoxide

With copper(ll) sulfate pentahydrate; cetyltrimethylammonim bromide; sodium hydrogencarbonate; sodium L-ascorbate; triethylamine; sodium hydroxide; In ethanol; dimethyl sulfoxide; toluene; acetonitrile;

DOI:10.1016/j.cclet.2010.11.029

upstream raw materials:

2-(2', 4'-difluorophenyl)-1-butylamino-3-(1''', 2''', 4''') triazol-1'''-yl-propan-2-ol

3-fluorobenzylazide

C₁₈H₂₂F₂N₄O

1,3-Difluorobenzene